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从白蜡树项目中汲取的经验教训,这是一个基因组学领域的众包公民科学游戏。

Lessons from Fraxinus, a crowd-sourced citizen science game in genomics.

作者信息

Rallapalli Ghanasyam, Saunders Diane Go, Yoshida Kentaro, Edwards Anne, Lugo Carlos A, Collin Steve, Clavijo Bernardo, Corpas Manuel, Swarbreck David, Clark Matthew, Downie J Allan, Kamoun Sophien, MacLean Dan

机构信息

The Sainsbury Laboratory, Norwich, United Kingdom.

The Genome Analysis Centre, Norwich, United Kingdom.

出版信息

Elife. 2015 Jul 29;4:e07460. doi: 10.7554/eLife.07460.

DOI:10.7554/eLife.07460
PMID:26219214
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4517073/
Abstract

In 2013, in response to an epidemic of ash dieback disease in England the previous year, we launched a Facebook-based game called Fraxinus to enable non-scientists to contribute to genomics studies of the pathogen that causes the disease and the ash trees that are devastated by it. Over a period of 51 weeks players were able to match computational alignments of genetic sequences in 78% of cases, and to improve them in 15% of cases. We also found that most players were only transiently interested in the game, and that the majority of the work done was performed by a small group of dedicated players. Based on our experiences we have built a linear model for the length of time that contributors are likely to donate to a crowd-sourced citizen science project. This model could serve a guide for the design and implementation of future crowd-sourced citizen science initiatives.

摘要

2013年,为应对前一年在英格兰爆发的白蜡树枯梢病疫情,我们推出了一款名为“白蜡树”的Facebook游戏,让非专业人士能够为导致该病的病原体以及受其侵害的白蜡树的基因组学研究做出贡献。在51周的时间里,玩家在78%的情况下能够匹配基因序列的计算比对,并在15%的情况下对其进行改进。我们还发现,大多数玩家只是对游戏短暂感兴趣,而且大部分工作是由一小群热心玩家完成的。基于我们的经验,我们构建了一个线性模型,用于预测贡献者可能为众包公民科学项目投入的时间长度。该模型可为未来众包公民科学倡议的设计和实施提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/889a39061879/elife07460fs008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/61bdd3d2f94b/elife07460f001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/a70dc74a9d49/elife07460fs007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/889a39061879/elife07460fs008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/61bdd3d2f94b/elife07460f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/d65e262134ed/elife07460fs001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/c356defaa501/elife07460fs002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/8516ba1a3b14/elife07460fs003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/43769611bddb/elife07460f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/a360b24706a8/elife07460fs004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/3579af23a2e9/elife07460fs005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/57499398cccb/elife07460f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/0023933fcb58/elife07460fs006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/a70dc74a9d49/elife07460fs007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a29/4517073/889a39061879/elife07460fs008.jpg

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2
Crowd science user contribution patterns and their implications.众包科学用户贡献模式及其影响。
Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):679-84. doi: 10.1073/pnas.1408907112. Epub 2015 Jan 5.
3
Changing the rules of the game.改变游戏规则。
CABI Agric Biosci. 2020;1(1):17. doi: 10.1186/s43170-020-00016-5. Epub 2020 Oct 30.
4
Designing Videogames to Crowdsource Accelerometer Data Annotation for Activity Recognition Research.设计电子游戏以众包加速度计数据注释用于活动识别研究。
Proc Annu Symp Comput Hum Interact Play. 2019 Oct;2019:135-147. doi: 10.1145/3311350.3347153.
5
Repurposing Citizen Science Games as Software Tools for Professional Scientists.将公民科学游戏重新用作专业科学家的软件工具。
FDG. 2018 Aug;2018. doi: 10.1145/3235765.3235770.
6
Can Gamification Contribute to Computer Modeling-Driven Biomedical Research?游戏化能否助力计算机建模驱动的生物医学研究?
Front Physiol. 2018 Jul 19;9:908. doi: 10.3389/fphys.2018.00908. eCollection 2018.
7
Harnessing citizen science through mobile phone technology to screen for immunohistochemical biomarkers in bladder cancer.利用移动电话技术的公民科学,筛选膀胱癌的免疫组织化学生物标志物。
Br J Cancer. 2018 Jul;119(2):220-229. doi: 10.1038/s41416-018-0156-0. Epub 2018 Jul 11.
8
Online Health Monitoring using Facebook Advertisement Audience Estimates in the United States: Evaluation Study.利用美国Facebook广告受众估计进行在线健康监测:评估研究
JMIR Public Health Surveill. 2018 Mar 28;4(1):e30. doi: 10.2196/publichealth.7217.
9
Collaborating with Undergraduates To Contribute to Biochemistry Community Resources.与本科生合作,为生物化学社区资源做贡献。
Biochemistry. 2018 Jan 30;57(4):383-389. doi: 10.1021/acs.biochem.7b00872. Epub 2017 Nov 2.
10
The diversity and evolution of ecological and environmental citizen science.生态与环境公民科学的多样性与演变
PLoS One. 2017 Apr 3;12(4):e0172579. doi: 10.1371/journal.pone.0172579. eCollection 2017.
Elife. 2013 Aug 13;2:e01294. doi: 10.7554/eLife.01294.
4
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J Gen Intern Med. 2014 Jan;29(1):187-203. doi: 10.1007/s11606-013-2536-8. Epub 2013 Jul 11.
5
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PLoS One. 2012;7(3):e31362. doi: 10.1371/journal.pone.0031362. Epub 2012 Mar 7.
7
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