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本文引用的文献

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Electron Microscopic Reconstruction of Functionally Identified Cells in a Neural Integrator.电子显微镜重建神经整合器中功能鉴定细胞。
Curr Biol. 2017 Jul 24;27(14):2137-2147.e3. doi: 10.1016/j.cub.2017.06.028. Epub 2017 Jul 14.
2
Foldit Standalone: a video game-derived protein structure manipulation interface using Rosetta.Foldit单机版:一个使用Rosetta的源自电子游戏的蛋白质结构操纵界面。
Bioinformatics. 2017 Sep 1;33(17):2765-2767. doi: 10.1093/bioinformatics/btx283.
3
Determining crystal structures through crowdsourcing and coursework.通过众包和课程作业确定晶体结构。
Nat Commun. 2016 Sep 16;7:12549. doi: 10.1038/ncomms12549.
4
Kinetic Characterization of 100 Glycoside Hydrolase Mutants Enables the Discovery of Structural Features Correlated with Kinetic Constants.100种糖苷水解酶突变体的动力学表征有助于发现与动力学常数相关的结构特征。
PLoS One. 2016 Jan 27;11(1):e0147596. doi: 10.1371/journal.pone.0147596. eCollection 2016.
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Saturated Reconstruction of a Volume of Neocortex.重建新皮层的体积
Cell. 2015 Jul 30;162(3):648-61. doi: 10.1016/j.cell.2015.06.054.
6
Lessons from Fraxinus, a crowd-sourced citizen science game in genomics.从白蜡树项目中汲取的经验教训,这是一个基因组学领域的众包公民科学游戏。
Elife. 2015 Jul 29;4:e07460. doi: 10.7554/eLife.07460.
7
Computational protein design enables a novel one-carbon assimilation pathway.计算蛋白质设计实现了一种新型的一碳同化途径。
Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3704-9. doi: 10.1073/pnas.1500545112. Epub 2015 Mar 9.
8
Space-time wiring specificity supports direction selectivity in the retina.时空布线特异性支持视网膜中的方向选择性。
Nature. 2014 May 15;509(7500):331-336. doi: 10.1038/nature13240. Epub 2014 May 4.
9
RNA design rules from a massive open laboratory.从大规模开放实验室中获得的 RNA 设计规则。
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2122-7. doi: 10.1073/pnas.1313039111. Epub 2014 Jan 27.
10
Computational design of an α-gliadin peptidase.α-麦醇溶蛋白肽酶的计算设计。
J Am Chem Soc. 2012 Dec 19;134(50):20513-20. doi: 10.1021/ja3094795. Epub 2012 Dec 5.

将公民科学游戏重新用作专业科学家的软件工具。

Repurposing Citizen Science Games as Software Tools for Professional Scientists.

作者信息

Cooper Seth, Sterling Amy L R, Kleffner Robert, Silversmith William M, Siegel Justin B

机构信息

Northeastern University,

Princeton University,

出版信息

FDG. 2018 Aug;2018. doi: 10.1145/3235765.3235770.

DOI:10.1145/3235765.3235770
PMID:30465045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6241531/
Abstract

Scientific software is often developed with scientists in mind, resulting in complex tools with a steep learning curve. , however, are designed for scientists- members of the general public. These games maintain scientific accuracy while placing design goals such as usability and enjoyment at the forefront. In this paper, we identify an emerging , in the repurposing of citizen science games to be software tools for professional scientists in their work. We discuss our experience in two such repurposings: Foldit, a protein folding and design game, and Eyewire, a web-based 3D neuron reconstruction game. Based on this experience, we provide evidence that the produced for citizen science can be useful for professional scientists, and provide an overview of key design principles we found to be useful in the process of repurposing.

摘要

科学软件的开发往往以科学家为目标用户,这使得这些工具复杂且学习曲线陡峭。然而,公民科学游戏是为普通公众中的“科学家”设计的。这些游戏在保持科学准确性的同时,将可用性和趣味性等设计目标置于首位。在本文中,我们发现了一种新趋势,即将公民科学游戏重新用作专业科学家工作中的软件工具。我们讨论了在两次这样的重新利用中的经验:Foldit,一款蛋白质折叠与设计游戏;以及Eyewire,一款基于网络的3D神经元重建游戏。基于这些经验,我们证明了为公民科学制作的内容对专业科学家可能有用,并概述了我们发现在重新利用过程中有用的关键设计原则。