用于纳米颗粒识别与计数的同步电光跟踪
Simultaneous Electro-Optical Tracking for Nanoparticle Recognition and Counting.
作者信息
Angeli Elena, Volpe Andrea, Fanzio Paola, Repetto Luca, Firpo Giuseppe, Guida Patrizia, Lo Savio Roberto, Wanunu Meni, Valbusa Ugo
机构信息
Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
Department of Physics and Chemistry/Chemical Biology, Northeastern University , Boston 02115, Massachusetts, United States.
出版信息
Nano Lett. 2015 Sep 9;15(9):5696-701. doi: 10.1021/acs.nanolett.5b01243. Epub 2015 Aug 5.
Abstract
We present the first detailed experimental observation and analysis of nanoparticle electrophoresis through a nanochannel obtained with synchronous high-bandwidth electrical and camera recordings. Optically determined particle diffusion coefficients agree with values extracted from fitting electrical transport measurements to distributions from 1D Fokker-Planck diffusion-drift theory. This combined tracking strategy enables optical recognition and electrical characterization of nanoparticles in solution, which can have a broad range of applications in biology and materials science.
摘要
我们展示了通过同步高带宽电学和摄像记录获得的纳米颗粒在纳米通道中电泳的首次详细实验观察与分析。光学测定的颗粒扩散系数与通过将电输运测量结果拟合到一维福克-普朗克扩散-漂移理论分布中提取的值相符。这种组合跟踪策略能够对溶液中的纳米颗粒进行光学识别和电学表征，这在生物学和材料科学中具有广泛的应用。
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