Seeing is believing: Ras dimers observed in live cells.
作者信息
Philips Mark R, Der Channing J
机构信息
Perlmutter Cancer Institute, New York University School of Medicine, New York, NY 10016;
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599
出版信息
Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9793-4. doi: 10.1073/pnas.1511805112. Epub 2015 Jul 30.
Abstract
摘要
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本文引用的文献
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Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7996-8001. doi: 10.1073/pnas.1509123112. Epub 2015 Jun 16.
2
GTP-Dependent K-Ras Dimerization.GTP 依赖的 K-Ras 二聚化
Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4.
3
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor.与一种细胞渗透性抑制剂结合的β-半乳糖苷酶的2.2埃分辨率冷冻电镜结构。
Science. 2015 Jun 5;348(6239):1147-51. doi: 10.1126/science.aab1576. Epub 2015 May 7.
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Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.致癌性和与RAS病相关的K-RAS突变可缓解效应器结合位点的膜依赖性封闭。
Proc Natl Acad Sci U S A. 2015 May 26;112(21):6625-30. doi: 10.1073/pnas.1419895112. Epub 2015 May 4.
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Drugging the undruggable RAS: Mission possible?靶向不可成药的 RAS：可能完成的任务？
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