Rabahi Marcelo Fouad, Pereira Sheila Alves, Silva Júnior José Laerte Rodrigues, de Rezende Aline Pacheco, Castro da Costa Adeliane, de Sousa Corrêa Krislainy, Conde Marcus Barreto
School of Medicine, Federal University of Goiás, Goiania, Brazil ; Clínica do Aparelho Respiratório (CLARE), Goiania, Brazil.
School of Medicine, Federal University of Goiás, Goiania, Brazil.
Int J Chron Obstruct Pulmon Dis. 2015 Jul 31;10:1525-9. doi: 10.2147/COPD.S85588. eCollection 2015.
The diagnosis of chronic obstructive pulmonary disease (COPD) is often delayed until later stages of the disease. The purpose of the present study was to determine the prevalence of COPD among adults on treatment for systemic arterial hypertension independently of the presence of respiratory symptoms.
This cross-sectional study included adults aged ≥40 years with tobacco/occupational exposure and systemic arterial hypertension diagnosed at three Primary Health Care facilities in Goiania, Brazil. Patients were evaluated using a standardized respiratory questionnaire and spirometry. COPD prevalence was measured considering the value of forced vital capacity and/or forced expiratory volume in 1 second <0.70.
Of a total of 570 subjects, 316 (55%) met inclusion criteria and were invited to participate. Two hundred and thirty-three (73.7%) patients with arterial hypertension reported at least one respiratory symptom, while 83 (26.3%) reported no respiratory symptoms; 41 (17.6%) patients with arterial hypertension and at least one respiratory symptom, and 10 (12%) patients with arterial hypertension but no respiratory symptoms were diagnosed with COPD (P=0.24). The prevalence of COPD in people with no previous COPD diagnosis was greater among those with no respiratory symptoms (100%) than among those with respiratory symptoms (56.1%) (P=0.01).
Our findings suggest that regardless of the presence of respiratory symptoms, individuals aged ≥40 years with tobacco/occupational exposure and arterial hypertension may benefit from spirometric evaluation.
慢性阻塞性肺疾病（COPD）的诊断往往会延迟到疾病的晚期。本研究的目的是确定在接受系统性动脉高血压治疗的成年人中COPD的患病率，而不考虑呼吸道症状的存在。
这项横断面研究纳入了年龄≥40岁、有烟草/职业暴露史且在巴西戈亚尼亚的三个初级卫生保健机构被诊断为系统性动脉高血压的成年人。使用标准化的呼吸问卷和肺活量测定法对患者进行评估。根据用力肺活量和/或1秒用力呼气量<0.70的值来测量COPD患病率。
在总共570名受试者中，316名（55%）符合纳入标准并被邀请参与。233名（73.7%）患有动脉高血压的患者报告了至少一种呼吸道症状，而83名（26.3%）报告无呼吸道症状；41名（17.6%）患有动脉高血压且至少有一种呼吸道症状的患者和10名（12%）患有动脉高血压但无呼吸道症状的患者被诊断为COPD（P = 0.24）。在既往未诊断出COPD的人群中，无呼吸道症状者的COPD患病率（100%）高于有呼吸道症状者（56.1%）（P = 0.01）。
我们的研究结果表明，无论是否存在呼吸道症状，年龄≥40岁、有烟草/职业暴露史且患有动脉高血压的个体可能从肺活量测定评估中获益。
