Koul Rashmi, Tse Richard, Karreman Erwin, Dubey Arbind, Tai Patricia
Radiation Oncologist, Department of Radiation Oncology, Allan Blair Cancer Center, 4101 Dewdney Ave, Regina, SK, Canada S4T7T1.
Regina Qu'Appelle Health Region, Regina, SK, Canada.
Int J Hematol Oncol Stem Cell Res. 2015 Jul 1;9(3):122-7.
The impact of treatment on cancer patients' quality of life (QoL) has been the focus of a variety of longitudinal studies in English literature for past decade. The measurement of patient-reported outcomes which includes health-related quality of life is a new important initiative which has emerged and grown over the past three decades. Following the development of reliable and valid self-reported questionnaires, health-related quality of life has been assessed in tens of thousands of patients and a wide variety of cancers. With growing information, feedback and experience, the quality of the health-related QOL studies has improved a lot. We expect in near future more methodologically robust studies will be done in a scientific way to answer unanswered questions.
As part of a Dean's summer project, a survey was undertaken to facilitate a more complete description of the quality of life experience in patients with histological diagnosis of cancer undergoing external beam radiation as an outpatient at Allan Blair Cancer Center, Regina, Canada. The questionnaires had two major components: depression and global QOL. The depression was measured by the Zung Self-Rating Depression Scale which is a short self-administered survey to quantify the depression status of a patient.
Overall, only the equation associated with the outcome of QoL - Physical well-being was significant. That data indicated that only the variable of age was a significant predictor. A positive relationship was present indicating higher levels of depression when patients received chemotherapy or narcotics. Breast cancer patients were less depressed than lung cancer patients.
Cancer and its related treatment is an important health issue influencing QoL. The study has revealed that the use of chemotherapy and narcotics has a significant impact on the quality of life (QoL).
在过去十年中,治疗对癌症患者生活质量(QoL)的影响一直是英文文献中各种纵向研究的重点。包括健康相关生活质量在内的患者报告结局的测量是过去三十年来出现并不断发展的一项新的重要举措。随着可靠且有效的自我报告问卷的发展,已在数以万计的患者和多种癌症中对健康相关生活质量进行了评估。随着信息、反馈和经验的不断增加,健康相关生活质量研究的质量有了很大提高。我们预计在不久的将来,将以科学的方式开展更多方法上更稳健的研究,以回答尚未解决的问题。
作为院长暑期项目的一部分,我们进行了一项调查,以便更全面地描述在加拿大里贾纳市艾伦·布莱尔癌症中心接受门诊外照射放疗的组织学诊断为癌症的患者的生活质量体验。问卷有两个主要部分:抑郁和总体生活质量。抑郁通过zung自评抑郁量表进行测量,这是一项简短的自我管理调查,用于量化患者的抑郁状态。
总体而言,只有与生活质量结果——身体健康相关的方程具有显著性。该数据表明只有年龄变量是一个显著的预测因素。存在正相关关系,表明患者接受化疗或使用麻醉药品时抑郁水平较高。乳腺癌患者的抑郁程度低于肺癌患者。
癌症及其相关治疗是影响生活质量的一个重要健康问题。该研究表明,化疗和麻醉药品的使用对生活质量(QoL)有显著影响。