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刚果民主共和国冲突地区基伍省的人间猴痘疫情

Human Monkeypox in the Kivus, a Conflict Region of the Democratic Republic of the Congo.

作者信息

McCollum Andrea M, Nakazawa Yoshinori, Ndongala Guy Mutombo, Pukuta Elisabeth, Karhemere Stomy, Lushima Robert Shongo, Ilunga Benoit Kebela, Kabamba Joelle, Wilkins Kimberly, Gao Jinxin, Li Yu, Emerson Ginny, Damon Inger K, Carroll Darin S, Reynolds Mary G, Malekani Jean, Tamfum Jean-Jacques Muyembe

机构信息

Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo

Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.

出版信息

Am J Trop Med Hyg. 2015 Oct;93(4):718-21. doi: 10.4269/ajtmh.15-0095. Epub 2015 Aug 17.

DOI:10.4269/ajtmh.15-0095
PMID:26283752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4596588/
Abstract

Monkeypox (MPX) is a zoonotic Orthopoxvirus infection endemic in central and western Africa. Human MPX cases occur in the central and northern regions of the Democratic Republic of the Congo (DRC), and this is the first report of confirmed MPX cases in the forested areas of North and South Kivu Provinces, with a detailed epidemiological investigation for one case. The location of each case is within areas predicted to be suitable for MPX virus transmission based on an ecological niche model. Phylogenetic analysis places these viruses in the Congo Basin clade.

摘要

猴痘是一种由正痘病毒引起的人畜共患病,在中非和西非呈地方性流行。人类猴痘病例发生在刚果民主共和国(DRC)的中部和北部地区,这是南北基伍省森林地区确诊猴痘病例的首次报告,并对其中一例进行了详细的流行病学调查。根据生态位模型,每个病例的位置都在预计适合猴痘病毒传播的区域内。系统发育分析将这些病毒归入刚果盆地分支。

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本文引用的文献

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Detection of human monkeypox in the Republic of the Congo following intensive community education.刚果共和国在强化社区教育后发现人感染猴痘病例。
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Phylogenetic and ecologic perspectives of a monkeypox outbreak, southern Sudan, 2005.2005 年,苏丹南部猴痘疫情的系统发生和生态透视。
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Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo.刚果民主共和国停止天花疫苗接种活动 30 年后,人类猴痘发病率大幅上升。
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Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA.实时 PCR 检测用于特异性检测猴痘病毒西非株和刚果盆地株 DNA。
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Endemic human monkeypox, Democratic Republic of Congo, 2001-2004.2001 - 2004年,刚果民主共和国的地方性人间猴痘
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