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短暂性脑缺血发作(TIA)的管理:TIA患者是否应住院治疗?TIA患者是否应接受联合抗血小板治疗?

TIA Management: Should TIA Patients be Admitted? Should TIA Patients Get Combination Antiplatelet Therapy?

作者信息

Mijalski Christina, Silver Brian

机构信息

Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Neurohospitalist. 2015 Jul;5(3):151-60. doi: 10.1177/1941874415580598.

DOI:10.1177/1941874415580598
PMID:26288673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4530421/
Abstract

Transient ischemic attack (TIA) has gained increasing attention over the last 2 decades with the realization that the condition is common, portends potentially serious consequences, and, when identified early, can be evaluated and treated to modify future risk. In this review, we examine the issues of whether all TIA patients need admission and whether such patients should receive short-term dual antiplatelet therapy. Not all patients require admission if evaluation and treatment are done promptly. There may be a role for dual antiplatelet therapy, but the results of further clinical trials will help provide better clarity on which patients are the best candidates for this treatment.

摘要

在过去20年里,短暂性脑缺血发作(TIA)日益受到关注,因为人们认识到这种疾病很常见,可能预示着潜在的严重后果,而且如果早期发现,可以进行评估和治疗以改变未来风险。在本综述中,我们探讨了所有TIA患者是否都需要住院以及此类患者是否应接受短期双重抗血小板治疗的问题。如果能迅速进行评估和治疗,并非所有患者都需要住院。双重抗血小板治疗可能有一定作用,但进一步临床试验的结果将有助于更清楚地确定哪些患者是这种治疗的最佳候选者。

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本文引用的文献

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Dual antiplatelet therapy after noncardioembolic ischemic stroke or transient ischemic attack: pros and cons.非心源性缺血性卒中和短暂性脑缺血发作后双联抗血小板治疗:利弊。
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ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack.ABCD3 和 ABCD3-I 评分在预测短暂性脑缺血发作后短期和长期卒中风险方面优于 ABCD2 评分。
Stroke. 2014 Feb;45(2):418-25. doi: 10.1161/STROKEAHA.113.003077. Epub 2013 Dec 12.
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N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19.
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