Heidemann D
Dtsch Zahnarztl Z. 1989 Jun;44(6):417-20.
The question of contact with the surface of biomaterials has not been fully elucidated. The importance of the surface structure continues to be discussed in terms of the roughness profile. However, it can be demonstrated that surface structure alone is not the crucial parameter for the adhesion or the lack of adhesion of cells. Probably factors like serum coating of a substrate and fibronectin formation of cells are at least as important, if not decisive preconditions for cell adhesion and in particular for the active spreading of cells in contact with biomaterials.
生物材料表面接触的问题尚未得到充分阐明。表面结构的重要性仍在根据粗糙度轮廓进行讨论。然而，可以证明，仅表面结构并非细胞黏附或不黏附的关键参数。底物的血清包被和细胞的纤连蛋白形成等因素可能至少同样重要，即便不是细胞黏附尤其是细胞与生物材料接触时的主动铺展的决定性先决条件。
