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三阴性乳腺癌的超声检查结果。

Ultrasonographic findings of triple-negative breast cancer.

作者信息

Du Hai-Yan, Lin Bao-Rong, Huang Du-Ping

机构信息

Department of Ultrasonography, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, China.

Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, China.

出版信息

Int J Clin Exp Med. 2015 Jun 15;8(6):10040-3. eCollection 2015.

PMID:26309697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4538191/
Abstract

OBJECTIVE

Our aim was to determine whether triple-negative breast cancer (TNBC) has distinguishing sonographic features compared to non-TNBC.

METHODS

Data from 145 consecutive breast cancer patients were collected. The images were reevaluated by two dedicated breast imaging experts according to the Breast Imaging Reporting and Data System. The sonographic features of 45 TNBC patients were compared with those of 100 non-TNBC patients.

RESULTS

TNBC showed a high histological tumor grade. On ultrasound, TNBC was more frequently to present as oval or round mass shape (48.9%, 17.8%; respectively), more likely to have circumscribed margins (82.2%), and less likely to show posterior attenuating (8.9%). Additionally, compared with non-TNBC, TNBC was less likely to have calcification (35.6%).

CONCLUSION

TNBC has distinguishing imaging features on breast ultrasound, and more likely to be associated with benign masses. Knowledge of the distinct sonographic features would be useful in diagnosing TNBC.

摘要

目的

我们的目的是确定三阴性乳腺癌(TNBC)与非三阴性乳腺癌相比是否具有独特的超声特征。

方法

收集了145例连续乳腺癌患者的数据。两名专业乳腺影像专家根据乳腺影像报告和数据系统对图像进行了重新评估。将45例TNBC患者的超声特征与100例非TNBC患者的超声特征进行了比较。

结果

TNBC显示出较高的组织学肿瘤分级。在超声检查中,TNBC更常表现为椭圆形或圆形肿块(分别为48.9%、17.8%),更有可能具有清晰的边界(82.2%),而不太可能出现后方衰减(8.9%)。此外,与非TNBC相比,TNBC出现钙化的可能性较小(35.6%)。

结论

TNBC在乳腺超声检查中具有独特的影像学特征,且更有可能与良性肿块相关。了解这些独特的超声特征将有助于TNBC的诊断。

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本文引用的文献

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Combined use of the automated breast volume scanner and the US elastography for the differentiation of benign from malignant lesions of the breast.自动乳腺容积扫描仪与超声弹性成像联合用于乳腺良恶性病变的鉴别诊断。
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Current clinical indications for magnetic resonance imaging of the breast.当前乳房磁共振成像的临床适应证。
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Triple-negative breast cancer and the need for new therapeutic targets.三阴性乳腺癌与新治疗靶点的需求
Am J Pathol. 2013 Oct;183(4):1064-1074. doi: 10.1016/j.ajpath.2013.05.033. Epub 2013 Aug 3.
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Ann Oncol. 2012 Aug;23 Suppl 6:vi13-8. doi: 10.1093/annonc/mds188.
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Sonographic features of triple-negative and non-triple-negative breast cancer.三阴性和非三阴性乳腺癌的超声特征。
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