Du Hai-Yan, Lin Bao-Rong, Huang Du-Ping
Department of Ultrasonography, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, China.
Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000, China.
Int J Clin Exp Med. 2015 Jun 15;8(6):10040-3. eCollection 2015.
Our aim was to determine whether triple-negative breast cancer (TNBC) has distinguishing sonographic features compared to non-TNBC.
Data from 145 consecutive breast cancer patients were collected. The images were reevaluated by two dedicated breast imaging experts according to the Breast Imaging Reporting and Data System. The sonographic features of 45 TNBC patients were compared with those of 100 non-TNBC patients.
TNBC showed a high histological tumor grade. On ultrasound, TNBC was more frequently to present as oval or round mass shape (48.9%, 17.8%; respectively), more likely to have circumscribed margins (82.2%), and less likely to show posterior attenuating (8.9%). Additionally, compared with non-TNBC, TNBC was less likely to have calcification (35.6%).
TNBC has distinguishing imaging features on breast ultrasound, and more likely to be associated with benign masses. Knowledge of the distinct sonographic features would be useful in diagnosing TNBC.
我们的目的是确定三阴性乳腺癌(TNBC)与非三阴性乳腺癌相比是否具有独特的超声特征。
收集了145例连续乳腺癌患者的数据。两名专业乳腺影像专家根据乳腺影像报告和数据系统对图像进行了重新评估。将45例TNBC患者的超声特征与100例非TNBC患者的超声特征进行了比较。
TNBC显示出较高的组织学肿瘤分级。在超声检查中,TNBC更常表现为椭圆形或圆形肿块(分别为48.9%、17.8%),更有可能具有清晰的边界(82.2%),而不太可能出现后方衰减(8.9%)。此外,与非TNBC相比,TNBC出现钙化的可能性较小(35.6%)。
TNBC在乳腺超声检查中具有独特的影像学特征,且更有可能与良性肿块相关。了解这些独特的超声特征将有助于TNBC的诊断。