J Investig Allergol Clin Immunol. 2015;25(4):270-5.
Specific food allergy quality of life questionnaires have been developed within the context of the EuroPrevall project. We aimed to adapt and validate the Food Allergy Quality of Life Questionnaire-Adult Form (FAQLQ-AF) in the Spanish language.
The original English questionnaire was translated and culturally adapted into Spanish following World Health Organization guidelines. The final Spanish version of the FAQLQ-AF (S-FAQLQ-AF) was approved by the original authors. Consecutive patients ( 18 years old) who fulfilled the following criteria were recruited: 1) diagnosis of food allergy defined as immediate allergic symptoms and a positive prick test or IgE against the culprit food(s) and 2) physician-assessed ability to complete the questionnaires. Patients completed the S-FAQLQ-AF and a Spanish version of the SF-12 questionnaire. Reliability was assessed 10 to 14 days after completion of the first questionnaire.
Eighty-two consecutive outpatients were recruited and cross-sectional validity was.assessed based on the correlation between the S-FAQLQ-AF and the Food Allergy Independent Measure (FAIM) in this population (rho = 0.83, P < .0001). The S-FAQLQ-AF showed excellent internal consistency (Cronbach α, 0.95). S-FAQLQ-AF domains also had excellent internal consistency: α = 0.93 for allergen avoidance-dietary restrictions; α = 0.83 for emotional impact; α = 0.85 for risk of accidental exposure, and α = 0.66 for food allergy related health. Limited correlation was found between the S-FAQLQ-AF and the SF-12.
The S-FAQLQ-AF is a valid, short, easy-to-use, and reliable instrument that discriminates between patients with different atopic phenotypes and is suitable for assessing the impact of IgE-mediated food allergy on patient quality of life.
特定食物过敏生活质量问卷已在 EuroPrevall 项目的背景下开发。我们旨在将成人食物过敏生活质量问卷(FAQLQ-AF)翻译成西班牙语并对其进行验证。
按照世界卫生组织的指南,将原始英文问卷翻译成西班牙文并进行文化适应性调整。FAQLQ-AF 的最终西班牙语版本(S-FAQLQ-AF)得到了原作者的认可。符合以下标准的连续患者(18 岁)被招募:1)食物过敏的诊断定义为过敏症状和阳性划痕试验或针对罪魁祸首食物的 IgE;2)医生评估能够完成问卷。患者完成 S-FAQLQ-AF 和西班牙语版的 SF-12 问卷。在完成第一个问卷后 10 到 14 天评估可靠性。
共招募了 82 名连续门诊患者,根据该人群中 S-FAQLQ-AF 与食物过敏独立测量(FAIM)之间的相关性评估了横断面有效性(rho=0.83,P<0.0001)。S-FAQLQ-AF 显示出极好的内部一致性(Cronbach α,0.95)。S-FAQLQ-AF 各领域也具有极好的内部一致性:过敏原回避-饮食限制领域的 α 值为 0.93;情感影响领域的 α 值为 0.83;意外暴露风险领域的 α 值为 0.85;食物过敏相关健康领域的 α 值为 0.66。S-FAQLQ-AF 与 SF-12 之间相关性有限。
S-FAQLQ-AF 是一种有效、简短、易用且可靠的工具,可区分不同特应性表型的患者,适用于评估 IgE 介导的食物过敏对患者生活质量的影响。