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使用胸腔积液样本的Xpert MTB/RIF检测法在胸膜结核诊断中的性能

Performance of Xpert MTB/RIF Assay in Diagnosis of Pleural Tuberculosis by Use of Pleural Fluid Samples.

作者信息

Rufai Syed Beenish, Singh Amit, Kumar Parveen, Singh Jitendra, Singh Sarman

机构信息

Division of Clinical Microbiology and Molecular Medicine, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India.

Division of Clinical Microbiology and Molecular Medicine, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India

出版信息

J Clin Microbiol. 2015 Nov;53(11):3636-8. doi: 10.1128/JCM.02182-15. Epub 2015 Aug 26.

Abstract

Prospectively, 162 pleural fluid samples from patients with probable tuberculous pleural effusion were tested by the Xpert MTB/RIF assay and the Bactec MGIT-960 culture system. Of these, 43 (26.5%) were positive in the MGIT-960 culture, and 23 (14.2%), in the Xpert MTB/RIF assay. The sensitivity and specificity of the Xpert MTB/RIF compared with the MGIT-960 culture were 54.8% and 100%, respectively.

摘要

前瞻性地,对162例疑似结核性胸腔积液患者的胸腔积液样本进行了Xpert MTB/RIF检测和Bactec MGIT - 960培养系统检测。其中,43例(26.5%)在MGIT - 960培养中呈阳性,23例(14.2%)在Xpert MTB/RIF检测中呈阳性。与MGIT - 960培养相比,Xpert MTB/RIF的敏感性和特异性分别为54.8%和100%。

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