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洗必泰、氟化钠、含精油氟化物、明矾、绿茶和大蒜与酸橙漱口水对致龋微生物的抗菌效果比较。

Comparison of the antimicrobial efficacy of chlorhexidine, sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses on cariogenic microbes.

作者信息

Thomas Ann, Thakur Sneha, Mhambrey Sanjana

机构信息

Department of Pedodontics and Preventive Dentistry, AJ Institute of Dental Sciences, Mangalore, Karnataka, India.

出版信息

J Int Soc Prev Community Dent. 2015 Jul-Aug;5(4):302-8. doi: 10.4103/2231-0762.161759.

Abstract

BACKGROUND

A number of natural mouth rinse formulations are being proposed as an alternative to the widely used chemical mouth rinses.

OBJECTIVE

To evaluate and compare the antimicrobial efficacy of chlorhexidine (0.2%), sodium fluoride (0.05%), fluoride with essential oils (0.05%), alum (0.02 M), green tea, and garlic with lime mouth rinses against Streptococcus mutans, lactobacilli, and Candida albicans.

MATERIALS AND METHODS

The three microbes were isolated from the saliva samples collected from children with severe early childhood caries. The zone of minimum inhibition was assessed using agar diffusion method. The data were statistically analyzed using SPSS software.

RESULTS

Against S. mutans and lactobacilli, chlorhexidine mouth rinse was found to be the most effective as compared to sodium fluoride (P < 0.001, P < 0.001), fluoride with essential oils (P < 0.001, P < 0.001), alum (P < 0.001, P < 0.001), green tea (P < 0.001, P < 0.001), and garlic with lime (P < 0.001, P < 0.001) mouth rinses, respectively. But against C. albicans, garlic with lime mouth rinse was found to be the most effective as compared to chlorhexidine (P < 0.001), sodium fluoride (P < 0.001), fluoride with essential oils (P < 0.001), alum (P < 0.001), and green tea (P < 0.001) mouth rinses. Against S. mutans and lactobacilli, after chlorhexidine mouth rinse, garlic with lime mouth rinse was found to be significantly more effective than sodium fluoride (P = 0.053, P = 0.001), fluoride with essential oils (P < 0.001, P < 0.001), alum (P < 0.001, P < 0.001), and green tea (P < 0.001, P < 0.001) mouth rinses.

CONCLUSION

As a natural mouth rinse, garlic with lime mouth rinse was found to be the most promising. However, further studies are needed in this field.

摘要

背景

许多天然漱口水配方被提议作为广泛使用的化学漱口水的替代品。

目的

评估并比较0.2%洗必泰、0.05%氟化钠、含精油的氟化物(0.05%)、明矾(0.02M)、绿茶以及大蒜加石灰漱口水对变形链球菌、乳酸菌和白色念珠菌的抗菌效果。

材料与方法

从患有严重幼儿龋齿的儿童唾液样本中分离出这三种微生物。采用琼脂扩散法评估最小抑菌圈。使用SPSS软件对数据进行统计分析。

结果

与氟化钠(P < 0.001,P < 0.001)、含精油的氟化物(P < 0.001,P < 0.001)、明矾(P < 0.001,P < 0.001)、绿茶(P < 0.001,P < 0.001)以及大蒜加石灰(P < 0.001,P < 0.001)漱口水相比,洗必泰漱口水对变形链球菌和乳酸菌最有效。但与洗必泰(P < 0.001)、氟化钠(P < 0.001)、含精油的氟化物(P < 0.001)、明矾(P < 0.001)和绿茶(P < 0.001)漱口水相比,大蒜加石灰漱口水对白色念珠菌最有效。对于变形链球菌和乳酸菌,在使用洗必泰漱口水后,发现大蒜加石灰漱口水比氟化钠(P = 0.053,P = 0.001)、含精油的氟化物(P < 0.001,P < 0.001)、明矾(P < 0.001,P < 0.001)和绿茶(P < 0.001,P < 0.001)漱口水显著更有效。

结论

作为一种天然漱口水,大蒜加石灰漱口水被认为最有前景。然而,该领域还需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6342/4547445/cd91dfda6b1a/JISPCD-5-302-g001.jpg

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