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含木糖醇、氟化钠和三氯生的漱口水对变形链球菌的影响。

Effect of xylitol, sodium fluoride and triclosan containing mouth rinse on Streptococcus mutans.

作者信息

Subramaniam Priya, Nandan N

机构信息

Department of Pedodontics, The Oxford Dental College, Hospital and Research Centre, Bangalore, India.

出版信息

Contemp Clin Dent. 2011 Oct;2(4):287-90. doi: 10.4103/0976-237X.91790.

Abstract

INTRODUCTION

Prevention of dental caries is one of the main strategies in contemporary pediatric dental practice. Mouth rinses are widely used as an adjunct to maintain oral hygiene. It is important for these products to be effective and safe for regular use in children.

OBJECTIVE

The aim of the study was to investigate the efficacy of a newly introduced xylitol, sodium fluoride and triclosan containing mouth rinse in reducing levels of plaque Streptococcus mutans and to compare it with that of a 0.12% chlorhexidine mouth rinse.

MATERIALS AND METHODS

Thirty children were randomly divided into two groups of 15 children each. Group I (study group) was given a mouth rinse containing xylitol (5%), sodium fluoride (0.05%) and triclosan (0.03%) and Group II (control group) was given a chlorhexidine (0.12%) mouth rinse. Both mouth rinses were alcohol free. Mouth rinsing was carried out twice daily, half an hour after breakfast and half an hour following dinner, for a period of 21 days under the supervision of the investigator.

RESULTS

In both groups, there was a significant reduction in the mean S. mutans count at the end of 21 days (P < 0.001). No significant difference was observed between the two mouth rinses.

CONCLUSION

The use of a low fluoride-xylitol based mouth rinse appears to be a suitable choice for regular use in children.

摘要

引言

预防龋齿是当代儿童牙科实践的主要策略之一。漱口水作为维持口腔卫生的辅助手段被广泛使用。这些产品对于儿童常规使用而言有效且安全很重要。

目的

本研究的目的是调查一种新推出的含木糖醇、氟化钠和三氯生的漱口水在降低变形链球菌菌斑水平方面的疗效,并将其与0.12%氯己定漱口水进行比较。

材料与方法

30名儿童被随机分为两组,每组15名儿童。第一组(研究组)使用含木糖醇(5%)、氟化钠(0.05%)和三氯生(0.03%)的漱口水,第二组(对照组)使用氯己定(0.12%)漱口水。两种漱口水均不含酒精。在研究者的监督下,每天早晚饭后半小时各进行一次漱口水含漱,持续21天。

结果

两组在21天结束时变形链球菌平均计数均显著降低(P < 0.001)。两种漱口水之间未观察到显著差异。

结论

使用低氟木糖醇基漱口水似乎是儿童常规使用的合适选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69ec/3276854/92e1e1300746/CCD-2-287-g002.jpg

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