基于金纳米粒子的纳米级谷胱甘肽比色传感的分散主导显色策略。
A Dispersion-Dominated Chromogenic Strategy for Colorimetric Sensing of Glutathione at the Nanomolar Level Using Gold Nanoparticles.
机构信息
Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.
University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
出版信息
Small. 2015 Nov 4;11(41):5510-4. doi: 10.1002/smll.201500903. Epub 2015 Aug 27.
A dispersion-dominated chromogenic strategy for glutathione sensing is developed. Glutathione prevents the aggregation of arginine-modified gold nanoparticles via mercury-thiol interaction, which allows for glutathione sensing at the nanomolar level (10.9 × 10(-9) m) with facile operation and naked-eye readout.
开发了一种基于分散控制的显色策略来检测谷胱甘肽。谷胱甘肽通过汞-硫醇相互作用阻止精氨酸修饰的金纳米粒子的聚集，从而可以在纳摩尔水平（10.9×10(-9) m）进行谷胱甘肽检测，操作简单，肉眼可读。
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