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按病因分类的教育水平与慢性肝病:一项比例死亡率研究。

Education level and chronic liver disease by aetiology: A proportional mortality study.

作者信息

Fedeli Ugo, Avossa Francesco, Goldoni Carlo Alberto, Caranci Nicola, Zambon Francesco, Saugo Mario

机构信息

SER - Epidemiological Department, Veneto Region, Italy.

SER - Epidemiological Department, Veneto Region, Italy.

出版信息

Dig Liver Dis. 2015 Dec;47(12):1082-5. doi: 10.1016/j.dld.2015.07.154. Epub 2015 Aug 7.

Abstract

BACKGROUND

Data are lacking on mortality from chronic liver diseases of different aetiology by education level.

AIMS

To investigate the association between education level and mortality from alcoholic, viral, and non-viral/non-alcoholic chronic liver disease.

METHODS

Proportional mortality was investigated in 2011-2013 in the Veneto Region (Italy). Odds ratios were estimated by conditional logistic regression with deaths from liver cirrhosis, liver cancer, and viral hepatitis as cases, and all other deaths as controls. Disease aetiology was determined from all conditions mentioned in the death certificate.

RESULTS

Overall chronic liver disease proportional mortality was higher in males (OR 1.37, 95% CI 1.18-1.60) and females (OR 1.72, 95% CI 1.29-2.30) with primary education than in subjects with higher educational level. The risk for alcohol-related and non-viral/non-alcohol-related disease significantly increased with lower education in both genders.

CONCLUSIONS

Proportional mortality analysis of multiple causes of death records showed an association between education and chronic liver diseases with alcoholic and non-viral/non-alcoholic aetiology.

摘要

背景

不同病因慢性肝病的死亡率按教育水平划分的数据尚缺。

目的

研究教育水平与酒精性、病毒性及非病毒性/非酒精性慢性肝病死亡率之间的关联。

方法

2011年至2013年在意大利威尼托地区调查比例死亡率。以肝硬化、肝癌和病毒性肝炎死亡病例为病例组,所有其他死亡为对照组,通过条件逻辑回归估计比值比。疾病病因根据死亡证明中提及的所有病症确定。

结果

接受小学教育的男性(比值比1.37,95%可信区间1.18 - 1.60)和女性(比值比1.72,95%可信区间1.29 - 2.30)总体慢性肝病比例死亡率高于受教育程度较高的人群。酒精相关和非病毒/非酒精相关疾病的风险在男女中均随教育程度降低而显著增加。

结论

对多种死因记录的比例死亡率分析显示,教育与酒精性及非病毒性/非酒精性病因的慢性肝病之间存在关联。

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