Santoro Nanette, Epperson C Neill, Mathews Sarah B
Department of Obstetrics & Gynecology, University of Colorado School of Medicine, 12631 East 17th Avenue, AO1, Room 4010, Aurora, CO 80045, USA.
Department of Psychiatry Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, 3rd Floor, Philadelphia, PA 19104-3309, USA.
Endocrinol Metab Clin North Am. 2015 Sep;44(3):497-515. doi: 10.1016/j.ecl.2015.05.001.
The menopause transition is associated with various symptoms, which can interact to produce morbidity. Vasomotor symptoms are the most commonly reported, but vaginal dryness/dyspareunia, sleep difficulties and adverse mood changes have all been shown to worsen as women approach menopause. For postmenopausal women changes in cognition are more likely to be related to aging and not to hormones. This article reviews the symptoms of hot flashes (vasomotor symptoms), vaginal dryness/dyspareunia, adverse mood, poor sleep/insomnia, and cognitive complaints, describing their epidemiology, diagnosis, and treatment. This article thus reviews the epidemiology, pathophysiology, diagnosis, and treatment of these common menopausal symptoms.
绝经过渡与各种症状相关,这些症状相互作用会导致发病。血管舒缩症状是最常报告的,但随着女性接近绝经,阴道干燥/性交困难、睡眠障碍和不良情绪变化均已显示会加重。对于绝经后女性,认知变化更可能与衰老有关,而非激素。本文综述潮热(血管舒缩症状)、阴道干燥/性交困难、不良情绪、睡眠不佳/失眠以及认知主诉的症状,描述其流行病学、诊断和治疗。因此,本文综述这些常见绝经症状的流行病学、病理生理学、诊断和治疗。