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监测孕妇中的艾滋病毒流行情况:当前措施是否足够?

Monitoring HIV Epidemic in Pregnant Women: Are the Current Measures Enough?

作者信息

Sarkate Purva, Paranjpe Supriya, Ingole Nayana, Mehta Preeti

机构信息

Department of Microbiology, Seth G. S. Medical College and KEM Hospital, Mumbai 400012, India.

出版信息

J Sex Transm Dis. 2015;2015:194831. doi: 10.1155/2015/194831. Epub 2015 Jan 19.

Abstract

Introduction. Burden of HIV in pregnant women follows overall epidemic in India. Hence, it is imperative that prevalence calculations in this group be accurate. The present study was carried out to determine prevalence of HIV in pregnant women attending our hospital, to determine trend of HIV infection and to compare our results with reported prevalence. Methods. All pregnant women are routinely counselled for HIV testing using opt-out strategy. Year-wise positivity and trend were determined in these patients over a period of five years. The positivity in different age groups was determined. Results. 31,609 women were tested of which 279 (0.88%) were positive. Positivity showed a declining trend over study period and significant quadratic trend (biphasic, P < 0.05) was observed. The positivity in older age group ≥35 years (1.64%) was significantly more than younger age groups (0.76% in 15-24-year and 0.94% in 25-34-year age group) (P = 0.0052). Conclusion. A significant decline in HIV positivity was seen over the study period. Taking into account heterogeneous nature of HIV epidemic even within the same district, analysis at local levels especially using the prevention of parent to child transmission of HIV program data is critical for HIV programming and resource allocation.

摘要

引言。印度孕妇群体中的艾滋病毒负担与整体疫情情况一致。因此,准确计算该群体中的艾滋病毒流行率至关重要。本研究旨在确定我院就诊孕妇中艾滋病毒的流行率,确定艾滋病毒感染趋势,并将我们的结果与报告的流行率进行比较。方法。所有孕妇均采用主动提供检测的策略接受艾滋病毒检测的常规咨询。在五年时间里确定这些患者逐年的阳性率及趋势。确定不同年龄组的阳性率。结果。共检测了31609名女性,其中279名(0.88%)呈阳性。在研究期间阳性率呈下降趋势,且观察到显著的二次趋势(双相,P < 0.05)。年龄≥35岁的老年组阳性率(1.64%)显著高于年轻组(15 - 24岁年龄组为0.76%,25 - 34岁年龄组为0.94%)(P = 0.0052)。结论。在研究期间观察到艾滋病毒阳性率显著下降。考虑到即使在同一地区艾滋病毒疫情的异质性,特别是利用预防艾滋病毒母婴传播项目数据进行地方层面的分析对于艾滋病毒规划和资源分配至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3efa/4437413/61cb632043c0/JSTD2015-194831.001.jpg

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