Opie R S, Itsiopoulos C, Parletta N, Sanchez-Villegas A, Akbaraly T N, Ruusunen A, Jacka F N
a School of Allied Health , College of Science, Health and Engineering, La Trobe University , Melbourne , Australia.
b International Society for Nutritional Psychiatry Research (ISNPR) , Melbourne , Australia.
Nutr Neurosci. 2017 Apr;20(3):161-171. doi: 10.1179/1476830515Y.0000000043. Epub 2016 Mar 2.
Major depressive disorder is a common, chronic condition that imposes a substantial burden of disability globally. As current treatments are estimated to address only one-third of the disease burden of depressive disorders, there is a need for new approaches to prevent depression or to delay its progression. While in its early stages, converging evidence from laboratory, population research, and clinical trials now suggests that dietary patterns and specific dietary factors may influence the risk for depression. However, largely as a result of the recency of the nutritional psychiatry field, there are currently no dietary recommendations for depression.
The aim of this paper is to provide a set of practical dietary recommendations for the prevention of depression, based on the best available current evidence, in order to inform public health and clinical recommendations.
Five key dietary recommendations for the prevention of depression emerged from current published evidence. These comprise: (1) follow 'traditional' dietary patterns, such as the Mediterranean, Norwegian, or Japanese diet; (2) increase consumption of fruits, vegetables, legumes, wholegrain cereals, nuts, and seeds; (3) include a high consumption of foods rich in omega-3 polyunsaturated fatty acids; (4) replace unhealthy foods with wholesome nutritious foods; (5) limit your intake of processed-foods, 'fast' foods, commercial bakery goods, and sweets.
Although there are a number of gaps in the scientific literature to date, existing evidence suggests that a combination of healthful dietary practices may reduce the risk of developing depression. It is imperative to remain mindful of any protective effects that are likely to come from the cumulative and synergic effect of nutrients that comprise the whole-diet, rather than from the effects of individual nutrients or single foods. As the body of evidence grows from controlled intervention studies on dietary patterns and depression, these recommendations should be modified accordingly.
重度抑郁症是一种常见的慢性疾病,在全球范围内造成了沉重的残疾负担。由于目前的治疗方法估计仅能解决抑郁症疾病负担的三分之一,因此需要新的方法来预防抑郁症或延缓其进展。虽然仍处于早期阶段,但来自实验室、人群研究和临床试验的越来越多的证据表明,饮食模式和特定饮食因素可能会影响抑郁症风险。然而,很大程度上由于营养精神病学领域尚新,目前尚无针对抑郁症的饮食建议。
本文的目的是根据目前可得的最佳证据,提供一套预防抑郁症的实用饮食建议,以便为公共卫生和临床建议提供参考。
根据目前已发表的证据,得出了五条预防抑郁症的关键饮食建议。这些建议包括:(1)遵循“传统”饮食模式,如地中海饮食、挪威饮食或日本饮食;(2)增加水果、蔬菜、豆类、全谷物、坚果和种子的摄入量;(3)大量食用富含ω-3多不饱和脂肪酸的食物;(4)用有益健康的营养食品替代不健康食品;(5)限制加工食品、“快餐”、商业烘焙食品和甜食的摄入量。
尽管迄今为止科学文献中存在一些空白,但现有证据表明,健康的饮食习惯相结合可能会降低患抑郁症的风险。必须牢记,任何保护作用可能来自构成整体饮食的营养素的累积和协同作用,而不是来自个别营养素或单一食物的作用。随着关于饮食模式与抑郁症的对照干预研究的证据越来越多,这些建议应相应修改。