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国际兽医癫痫特别工作组关于特定于兽医癫痫的MRI方案的建议。

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol.

作者信息

Rusbridge Clare, Long Sam, Jovanovik Jelena, Milne Marjorie, Berendt Mette, Bhatti Sofie F M, De Risio Luisa, Farqhuar Robyn G, Fischer Andrea, Matiasek Kaspar, Muñana Karen, Patterson Edward E, Pakozdy Akos, Penderis Jacques, Platt Simon, Podell Michael, Potschka Heidrun, Stein Veronika M, Tipold Andrea, Volk Holger A

机构信息

Fitzpatrick Referrals, Halfway Lane, Eashing, Godalming, GU7 2QQ, Surrey, UK.

School of Veterinary Medicine, Faculty of Health & Medical Sciences, University of Surrey, Guildford, GU2 7TE, Surrey, UK.

出版信息

BMC Vet Res. 2015 Aug 28;11:194. doi: 10.1186/s12917-015-0466-x.

Abstract

Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy. However, given that the diagnosis requires the exclusion of other differentials for seizures, the parameters for MRI examination should allow the detection of subtle lesions which may not be obvious with existing techniques. In addition, there are several differentials for idiopathic epilepsy in humans, for example some focal cortical dysplasias, which may only apparent with special sequences, imaging planes and/or particular techniques used in performing the MRI scan. As a result, there is a need to standardize MRI examination in veterinary patients with techniques that reliably diagnose subtle lesions, identify post-seizure changes, and which will allow for future identification of underlying causes of seizures not yet apparent in the veterinary literature.There is a need for a standardized veterinary epilepsy-specific MRI protocol which will facilitate more detailed examination of areas susceptible to generating and perpetuating seizures, is cost efficient, simple to perform and can be adapted for both low and high field scanners. Standardisation of imaging will improve clinical communication and uniformity of case definition between research studies. A 6-7 sequence epilepsy-specific MRI protocol for veterinary patients is proposed and further advanced MR and functional imaging is reviewed.

摘要

癫痫是兽医临床实践中最常见的慢性神经疾病之一。磁共振成像(MRI)被视为诊断特发性癫痫的一项重要诊断检查。然而,鉴于该诊断需要排除其他导致癫痫发作的病因,MRI检查参数应能检测出用现有技术可能不明显的细微病变。此外,人类特发性癫痫有多种鉴别诊断,例如一些局灶性皮质发育异常,可能只有在进行MRI扫描时采用特殊序列、成像平面和/或特定技术才会显现。因此,有必要对兽医患者的MRI检查进行标准化,采用能可靠诊断细微病变、识别癫痫发作后变化且能在未来确定兽医文献中尚未明确的癫痫发作潜在病因的技术。需要一种标准化的兽医癫痫专用MRI方案,该方案将有助于更详细地检查易引发和持续癫痫发作的区域,具有成本效益、操作简单,并且可适用于低场和高场扫描仪。成像标准化将改善临床沟通以及研究之间病例定义的一致性。本文提出了一种适用于兽医患者的6 - 7序列癫痫专用MRI方案,并对进一步的先进MR和功能成像进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f16/4594743/edcc427d217c/12917_2015_466_Fig1_HTML.jpg

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