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房颤(AF)同期手术消融术后植入式循环记录仪监测:来自200多名持续监测患者的见解

Implantable loop recorder monitoring after concomitant surgical ablation for atrial fibrillation (AF): insights from more than 200 continuously monitored patients.

作者信息

Pecha Simon, Aydin Muhammet Ali, Ahmadzade Teymour, Hartel Friederike, Hoffmann Boris, Steven Daniel, Willems Stephan, Reichenspurner Hermann, Wagner Florian Mathias

机构信息

Department of Cardiovascular Surgery, University Heart Center Hamburg, Martinistr. 52, 20246, Hamburg, Germany.

Department of Cardiology, St. Adolf-Stift Hospital Reinbek, Reinbek, Germany.

出版信息

Heart Vessels. 2016 Aug;31(8):1347-53. doi: 10.1007/s00380-015-0735-4. Epub 2015 Aug 29.

Abstract

Different follow-up methods have been used to report success rates after AF ablation. Recent studies have shown that intermittent rhythm monitoring underestimates the actual AF recurrence rate. We therefore report our experience with continuous rhythm monitoring by implantable loop recorder (ILR) in a large patient cohort. Between 09/2008 and 12/2012, 343 cardiac surgical patients underwent concomitant surgical AF ablation. ILR implantation was performed in 206 patients. ILR interrogation was accomplished at 3, 6 and 12 months postoperatively. Successful ablation was defined as AF Burden <0.5 %. Primary outcome of the study was freedom from AF at 12-month follow-up. Mean patient's age was 70.5 ± 7.4 years. No major ablation- or ILR-related complications occurred. In 4 patients (1.9 %) ILR had to be explanted due to ILR-related wound infection (n = 2) or chronic pain (n = 2). Survival rate at 1-year follow-up was 96.6 %. Freedom from AF rate after 1-year follow-up was 68.5 and 63.6 % off antiarrhythmic drugs, respectively. Statistically significant predictors for successful ablation at 1-year follow-up were smaller LA diameter, shorter duration of AF and preoperative paroxysmal AF. Demographic data, indication for surgery, lesion set and used energy source had no impact on freedom from AF after 1 year. Continuous ILR monitoring after concomitant surgical AF ablation was safe and feasible, with registered freedom from AF rate of 68.5 % at 1-year follow-up. Thus continuous rhythm monitoring provides reliable outcome data and helps to guide antiarrhythmic therapy.

摘要

不同的随访方法被用于报告房颤消融术后的成功率。近期研究表明,间歇性心律监测会低估实际的房颤复发率。因此,我们报告了在一大群患者中使用植入式循环记录仪(ILR)进行连续心律监测的经验。在2008年9月至2012年12月期间,343例心脏外科手术患者同时接受了外科房颤消融术。206例患者植入了ILR。术后3、6和12个月进行ILR问询。成功消融定义为房颤负荷<0.5%。该研究的主要结局是12个月随访时无房颤。患者平均年龄为70.5±7.4岁。未发生与消融或ILR相关的重大并发症。4例患者(1.9%)因ILR相关的伤口感染(n = 2)或慢性疼痛(n = 2)而不得不取出ILR。1年随访时的生存率为96.6%。1年随访后,停用抗心律失常药物时无房颤率分别为68.5%和63.6%。1年随访时成功消融的统计学显著预测因素为左心房直径较小、房颤持续时间较短和术前阵发性房颤。人口统计学数据、手术指征、消融灶和使用的能量来源对1年后无房颤情况无影响。外科房颤消融术后连续ILR监测安全可行,1年随访时记录的无房颤率为68.5%。因此,连续心律监测可提供可靠的结局数据并有助于指导抗心律失常治疗。

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