非分裂细胞中的中心体定位。
Centrosome positioning in non-dividing cells.
作者信息
Barker Amy R, McIntosh Kate V, Dawe Helen R
机构信息
Biosciences, College of Life and Environmental Sciences, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK.
Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, EC1M 6BQ, London.
出版信息
Protoplasma. 2016 Jul;253(4):1007-21. doi: 10.1007/s00709-015-0883-5. Epub 2015 Aug 30.
Centrioles and centrosomes are found in almost all eukaryotic cells, where they are important for organising the microtubule cytoskeleton in both dividing and non-dividing cells. The spatial location of centrioles and centrosomes is tightly controlled and, in non-dividing cells, plays an important part in cell migration, ciliogenesis and immune cell functions. Here, we examine some of the ways that centrosomes are connected to other organelles and how this impacts on cilium formation, cell migration and immune cell function in metazoan cells.
中心粒和中心体几乎存在于所有真核细胞中，它们对于在分裂细胞和非分裂细胞中组织微管细胞骨架都很重要。中心粒和中心体的空间位置受到严格控制，并且在非分裂细胞中，它们在细胞迁移、纤毛发生和免疫细胞功能中发挥重要作用。在这里，我们研究了中心体与其他细胞器相连的一些方式，以及这如何影响后生动物细胞中的纤毛形成、细胞迁移和免疫细胞功能。
Zotero 插件