Edia-Asuke Agnes Uregwu, Inabo Helen I, Mukaratirwa Samson, Umoh Veronica J, Whong Clement M Z, Asuke Sunday, Ella Elijah Ekah
Ahmadu Bello University, Samaru, Zaria, Kaduna, Nigeria.
J Infect Dev Ctries. 2015 Aug 29;9(8):799-805. doi: 10.3855/jidc.5415.
Taenia solium cysticercosis is considered an emerging parasitic zoonosis of global importance due to its impact on both agriculture and public health in developing countries. Epidemiological information on human cysticercosis is limited in Nigeria. This study was conducted to determine the seroprevalence of human cysticercosis in areas of Kaduna metropolis, Nigeria, where small-holder pig farming is practiced.
A cross-sectional survey was conducted in Kaduna South and Chikun Local Government Areas of Kaduna metropolis, which are widely involved in small-holder pig farming and pork consumption. A total of 300 human sera were collected and tested for the presence of IgG antibodies to T. solium using an enzyme-linked immunosorbent assay (ELISA) technique. A structured questionnaire was used to identify risk factors in the population and was administered to the study population.
A total of 43 of 300 sera tested positive to IgG antibodies, indicating a cysticercosis prevalence of 14.3%. Method of pork preparation and history of epilepsy were found to be strongly associated with seropositivity. Epileptics in this study were two times more likely to be seropositive than non-epileptics. A large proportion (74.0%) of the population had very poor knowledge of cysticercosis, and knowledge of cysticercosis was strongly associated with method of pork preparation and respondents' occupations.
A high seroprevalence of human cysticercosis was found in Kaduna South and Chikun Local Government Areas. The main risk and behavioral factors contributing to the high prevalence include poor knowledge of cysticercosis and lack of knowledge on proper pork preparation methods.
由于猪带绦虫囊尾蚴病对发展中国家的农业和公共卫生都有影响，它被认为是一种具有全球重要性的新兴寄生虫人畜共患病。在尼日利亚，关于人类囊尾蚴病的流行病学信息有限。本研究旨在确定尼日利亚卡杜纳市从事小规模养猪的地区人类囊尾蚴病的血清流行率。
在卡杜纳市南部和奇昆地方政府地区进行了一项横断面调查，这些地区广泛参与小规模养猪和猪肉消费。共收集了300份人类血清，并使用酶联免疫吸附测定（ELISA）技术检测是否存在抗猪带绦虫IgG抗体。使用结构化问卷来识别研究人群中的危险因素，并对研究人群进行调查。
300份血清中共有43份对IgG抗体检测呈阳性，表明囊尾蚴病患病率为14.3%。发现猪肉制备方法和癫痫病史与血清阳性密切相关。本研究中癫痫患者血清呈阳性的可能性是非癫痫患者的两倍。很大一部分（74.0%）人群对囊尾蚴病的了解非常少，并且对囊尾蚴病的了解与猪肉制备方法和受访者职业密切相关。
在卡杜纳市南部和奇昆地方政府地区发现人类囊尾蚴病的血清流行率很高。导致高流行率的主要风险和行为因素包括对囊尾蚴病的了解不足以及对正确猪肉制备方法的知识缺乏。
