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[在安齐拉贝地区转诊医院接受检查的一组患者中囊尾蚴病的血清流行率及相关危险因素]

[Seroprevalence of cysticercosis and associated risk factors in a group of patients examined at the Regional Referral Hospital in Antsirabe].

作者信息

Zafindraibe Norosoa Julie, Ralalarinivo Jeannine, Rakotoniaina Andriamiarimbola Irène, Maeder Muriel Nirina, Andrianarivelo Mala Rakoto, Contamin Bénedicte, Michault Alain, Rasamindrakotroka Andry

机构信息

Centre d'Infectiologie Charles Mérieux, Antananarivo, Madagascar.

Faculté de Médecine, Université d'Antananarivo, Madagascar.

出版信息

Pan Afr Med J. 2017 Nov 23;28:260. doi: 10.11604/pamj.2017.28.260.10463. eCollection 2017.

Abstract

INTRODUCTION

In Madagascar, cysticercosis, a disease caused by Taenia Solium's larval form, is a public health problem. In 2003, the seroprevalence of cysticercosis ranged between 7% and 21% with a higher rate in the central regions of the island. However, epidemiological data on human cysticercosis have been limited over the last dozen years. The objective of our study aimed to determine the seroprevalence of cysticercosis Western blot as well as its associated risk factors in patients from the region of Vakinankaratra with clinical suspicion.

METHODS

We conducted a cross-sectional, descriptive study at the Regional Referral Hospital in Antsirabe over a period of 6 months. All the patients included in the study answered a clinic questionnaire collecting their socio-demographic and cultural features as well as their dietary habits and their clinical symptoms.

RESULTS

The seroprevalence of cysticercosis in the study population was 14.8% (35/237). These rates did not differ significantly according to sex, age, pork consumption or meat preparation (p > 0.05). However, a significant difference (p < 0.05) was observed among patients with subcutaneous nodules or positive for cysticercosis.

CONCLUSION

In our study, the high index of exposure to Taenia solium justifies the strengthening of control and prevention measures already set up in our country.

摘要

引言

在马达加斯加,囊尾蚴病是由猪带绦虫幼虫引起的一种疾病,是一个公共卫生问题。2003年,囊尾蚴病的血清阳性率在7%至21%之间,该岛中部地区的发病率更高。然而,在过去十几年里,关于人类囊尾蚴病的流行病学数据一直有限。我们研究的目的是确定瓦基南卡拉特拉地区临床疑似患者中囊尾蚴病免疫印迹法的血清阳性率及其相关危险因素。

方法

我们在安齐拉贝地区转诊医院进行了一项为期6个月的横断面描述性研究。纳入研究的所有患者都回答了一份临床问卷,收集他们的社会人口学和文化特征、饮食习惯以及临床症状。

结果

研究人群中囊尾蚴病的血清阳性率为14.8%(35/237)。这些比率在性别、年龄、猪肉消费或肉类加工方面没有显著差异(p>0.05)。然而,在有皮下结节或囊尾蚴病呈阳性的患者中观察到显著差异(p<[0.05])。

结论

在我们的研究中,猪带绦虫的高暴露指数证明了加强我国已制定的控制和预防措施的合理性。

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