Ford Chandra L, Mulatu Mesfin S, Godette Dionne C, Gaines Tommi L
University of California at Los Angeles, Fielding School of Public Health, Department of Community Health Sciences, Los Angeles, CA.
Centers for Disease Control and Prevention, Division of HIV/AIDS Prevention, Atlanta, GA.
Public Health Rep. 2015 Sep-Oct;130(5):514-25. doi: 10.1177/003335491513000514.
This study examined temporal trends in HIV testing among U.S. older adults (50-64 years of age) before and after the release of CDC's routine HIV testing recommendations in 2006.
The sample (n=872,797; 51.4% female) comprised 2003-2010 Behavioral Risk Factor Surveillance System respondents in the oldest categories to which the recommendations apply: 50-54 years (34.5%, n=301,519), 55-59 years (34.1%, n=297,865), and 60-64 years (31.3%, n=273,413). We calculated (1) four-year pooled prevalences of past-year HIV testing before and after 2006, when the recommendations were released; and (2) annual prevalences of HIV testing overall and by age category from 2003-2010. Using weighted, multivariable logistic regression analyses, we examined binary (pre- vs. post-recommendations) and annual changes in testing, controlling for covariates. We stratified the data by recent doctor visits, examined racial/ethnic differences, and tested for linear and quadratic temporal trends.
Overall and within age categories, the pooled prevalence of past-year HIV testing decreased following release of the recommendations (p<0.001). The annual prevalence decreased monotonically from 2003 (5.5%) to 2006 (3.6%) (b=-0.16, p<0.001) and then increased immediately after release of the recommendations, but decreased to 3.7% after 2009 (b=0.01, p<0.001). By race/ethnicity, testing increased over time among non-Hispanic black people only. Annual prevalence also increased among respondents with recent doctor visits.
CDC's HIV testing recommendations were associated with a reversal in the downward trend in past-year HIV testing among older adults; however, the gains were neither universal nor sustained over time.
本研究调查了2006年美国疾病控制与预防中心(CDC)发布常规HIV检测建议前后,美国老年人(50 - 64岁)中HIV检测的时间趋势。
样本(n = 872,797;51.4%为女性)包括2003 - 2010年行为危险因素监测系统中年龄最大的符合该建议适用类别的受访者:50 - 54岁(34.5%,n = 301,519)、55 - 59岁(34.1%,n = 297,865)和60 - 64岁(31.3%,n = 273,413)。我们计算了:(1)2006年建议发布前后过去一年HIV检测的四年合并患病率;(2)2003 - 2010年总体及按年龄类别划分的HIV检测年度患病率。使用加权多变量逻辑回归分析,我们研究了检测的二元变化(建议发布前与发布后)和年度变化,并对协变量进行了控制。我们按近期看医生情况对数据进行分层,检查种族/民族差异,并检验线性和二次时间趋势。
总体及各年龄类别中,建议发布后过去一年HIV检测的合并患病率下降(p < 0.001)。年度患病率从2003年(5.5%)到2006年(3.6%)单调下降(b = -0.16,p < 0.001),建议发布后立即上升,但在2009年后降至3.7%(b = 0.01,p < 0.001)。按种族/民族划分,仅非西班牙裔黑人的检测率随时间增加。近期看医生的受访者中年度患病率也有所增加。
CDC的HIV检测建议与过去一年HIV检测下降趋势的逆转相关;然而,这种增加既不普遍,也未随时间持续。