Roberts Hannah, Ben-Shoshan Moshe
Department of Pediatrics, Janeway Children's Hospital, 300 Prince Phillip Drive, St. John's, Newfoundland and Labrador, A1B 3V6, Canada.
Division of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, Montreal, Quebec, Canada.
J Med Case Rep. 2015 Sep 3;9:186. doi: 10.1186/s13256-015-0669-6.
Food-dependent exercise-induced anaphylaxis is a subtype of anaphylaxis and, although rare, it is an important condition to be familiar with as it can ultimately lead to death.
We present a case of food-dependent exercise-induced anaphylaxis in a 17-year-old white girl due to chickpea. She had a history of anaphylaxis after eating crackers and hummus before exercising. Skin prick testing and serum-specific immunoglobulin E level confirmed chickpea to be the causative allergen.
This case demonstrates the challenge in identifying specific causative food allergens when foods are eaten in combination, when the food is processed, and when cross-reactivity is possible. These challenges add complexity to a condition that is already rare and unfamiliar to some health care providers. We hope that this case will serve as an important reminder that although rare, food-dependent exercise-induced anaphylaxis exists and making a diagnosis can lead to life-saving preventative strategies. As legumes are not a common food associated with food-dependent exercise-induced anaphylaxis, this will add to our current knowledge base in the field of allergy.
食物依赖运动诱发的过敏反应是过敏反应的一种亚型,尽管罕见,但它是一种需要熟悉的重要病症,因为它最终可能导致死亡。
我们报告一例17岁白人女孩因鹰嘴豆引发的食物依赖运动诱发的过敏反应。她有在运动前食用饼干和鹰嘴豆泥后发生过敏反应的病史。皮肤点刺试验和血清特异性免疫球蛋白E水平证实鹰嘴豆是致病过敏原。
该病例表明,当食物混合食用、经过加工以及可能存在交叉反应时,识别特定的致病食物过敏原具有挑战性。这些挑战给这种本就罕见且一些医疗服务提供者并不熟悉的病症增添了复杂性。我们希望这个病例能起到重要的警示作用,即尽管食物依赖运动诱发的过敏反应罕见,但确实存在,做出诊断可带来挽救生命的预防策略。由于豆类并非与食物依赖运动诱发的过敏反应相关的常见食物,这将增加我们在过敏领域的现有知识储备。