Keyes Paul H, Rams Thomas E, Jordan Harold V
formerly National Institute of Dental Research, National Institutes of Health, Bethesda, MD, USA.
Department of Periodontics, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.
Newsl Int Acad Periodontol. 1992 Mar;2(1):5-11.
The effect of two diets, with and without the antibiotic spiramycin, on -induced experimental periodontitis was studied in albino hamsters. Severe periodontitis and root caries developed in -infected hamsters fed a high sucrose diet. Hamsters heavily infected with but fed a finely powdered laboratory chow comprised of whole grains and oats formed discrete marginal plaques, but did not develop periodontitis. was not recovered from the plaque microflora of animals receiving spiramycin, and periodontal pathosis did not occur. These findings suggest that dietobacterial interactions and spiramycin may influence initiation of -associated periodontitis in albino hamsters.
在白化仓鼠中研究了两种饮食(含抗生素螺旋霉素和不含抗生素螺旋霉素)对诱导性实验性牙周炎的影响。喂食高蔗糖饮食的感染仓鼠会发展为严重的牙周炎和根龋。大量感染但喂食由全谷物和燕麦组成的精细粉状实验室饲料的仓鼠形成了离散的边缘菌斑,但未发展为牙周炎。在接受螺旋霉素的动物的菌斑微生物群中未检测到,并且未发生牙周病变。这些发现表明饮食-细菌相互作用和螺旋霉素可能会影响白化仓鼠中与相关的牙周炎的发生。