Torii Keiko U
Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195-1800, USA; Department of Biology, University of Washington, Seattle, WA 98195-1800, USA; Institute of Transformative Biomolecules, Nagoya University, Nagoya, Aichi 464-8601, Japan.
Curr Opin Plant Biol. 2015 Dec;28:16-22. doi: 10.1016/j.pbi.2015.08.005. Epub 2015 Sep 5.
Differentiation of stomata follows a series of stereotypical cell divisions and cell-state transitional steps specified by the master-regulatory transcription factors. The density and numbers of stomata are regulated by cell-cell signaling and flexibly modulated by environmental and physiological inputs. This review focuses on the latest breakthroughs in Arabidopsis elucidating the mechanisms behind the initiation of stomatal precursors, asymmetric cell division and stem cell behavior, and terminal differentiation of guard cells. I discuss new insights emerging from these studies: (i) competitive actions of signals and regulatory circuits initiating stomatal precursor pattern; (ii) a subcellular partitioning of signaling components determining the stomatal lineage stem-cell divisions; and (iii) epigenetic regulation maintaining the differentiated guard cell state.
气孔的分化遵循由主调控转录因子指定的一系列定型细胞分裂和细胞状态转变步骤。气孔的密度和数量受细胞间信号传导调控，并受到环境和生理输入的灵活调节。本综述聚焦于拟南芥在阐明气孔前体起始、不对称细胞分裂和干细胞行为以及保卫细胞终末分化背后机制方面的最新突破。我将讨论这些研究中出现的新见解：（i）启动气孔前体模式的信号和调控回路的竞争作用；（ii）决定气孔谱系干细胞分裂的信号成分的亚细胞分区；以及（iii）维持分化保卫细胞状态的表观遗传调控。
