Antoni D, Srour I, Mornex F
Département universitaire de radiothérapie, Unicancer, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg cedex, France; Laboratoire EA 3430, fédération de médecine translationnelle de Strasbourg (FMTS), université de Strasbourg, 67062 Strasbourg, France.
Département universitaire de radiothérapie, Unicancer, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg cedex, France.
Cancer Radiother. 2015 Oct;19(6-7):371-6. doi: 10.1016/j.canrad.2015.06.014. Epub 2015 Sep 7.
Stereotactic body radiation therapy for lung cancer is now well established for patients who are not eligible to surgery. These patients can benefit from a curative treatment, which is a new therapeutic indication. Protocols are effective and well tolerated even for the most fragile patients. Three randomized trials comparing stereotactic body radiation therapy and surgery failed due to poor accrual. However, taking into account the favourable available data, the choice of stereotactic body radiation therapy in first intention arises. The treatment decision has to be discussed in a multidisciplinary way, while considering the opinion of the patient, who must be clearly informed about the principle of both therapeutic options.
立体定向体部放射治疗现已成为不适于手术的肺癌患者的成熟治疗方法。这些患者可受益于一种根治性治疗，这是一种新的治疗指征。即使对于最脆弱的患者，治疗方案也是有效的且耐受性良好。三项比较立体定向体部放射治疗与手术的随机试验因入组不佳而失败。然而，考虑到现有的有利数据，首选立体定向体部放射治疗成为可能。治疗决策必须以多学科方式进行讨论，同时考虑患者的意见，必须向患者清楚地告知两种治疗选择的原则。
