Asao T, Fukuda T, Yazawa S, Nagamachi Y
First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan.
Cancer Lett. 1989 Sep 15;47(1-2):79-81. doi: 10.1016/0304-3835(89)90180-8.
Carcinoembryonic antigen (CEA) levels were determined in the peritoneal washings from 44 patients with gastric cancer to evaluate the usefulness for a predictor of postsurgical prognosis. Seventeen of the 21 patients (80.9%) with serosal invasion showed elevated levels of CEA, whereas most of the patients with no serosal invasion (22/23) showed low levels of CEA and did not develop peritoneal metastasis. All patients with positive cytology showed elevated levels of CEA in the peritoneal washings. Therefore, CEA levels in the peritoneal washings could be an adjunctive tool for predicting the postsurgical prognosis in gastric cancer.
检测了44例胃癌患者腹腔冲洗液中的癌胚抗原(CEA)水平,以评估其作为术后预后预测指标的有效性。21例浆膜侵犯患者中有17例(80.9%)CEA水平升高,而大多数无浆膜侵犯的患者(22/23)CEA水平较低且未发生腹膜转移。所有细胞学检查阳性的患者腹腔冲洗液中CEA水平均升高。因此,腹腔冲洗液中的CEA水平可作为预测胃癌术后预后的辅助工具。