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胃癌患者腹腔灌洗液中的癌胚抗原水平作为预后指标。

CEA levels in peritoneal washings from gastric cancer patients as a prognostic guide.

作者信息

Asao T, Fukuda T, Yazawa S, Nagamachi Y

机构信息

First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan.

出版信息

Cancer Lett. 1989 Sep 15;47(1-2):79-81. doi: 10.1016/0304-3835(89)90180-8.

DOI:10.1016/0304-3835(89)90180-8
PMID:2636035
Abstract

Carcinoembryonic antigen (CEA) levels were determined in the peritoneal washings from 44 patients with gastric cancer to evaluate the usefulness for a predictor of postsurgical prognosis. Seventeen of the 21 patients (80.9%) with serosal invasion showed elevated levels of CEA, whereas most of the patients with no serosal invasion (22/23) showed low levels of CEA and did not develop peritoneal metastasis. All patients with positive cytology showed elevated levels of CEA in the peritoneal washings. Therefore, CEA levels in the peritoneal washings could be an adjunctive tool for predicting the postsurgical prognosis in gastric cancer.

摘要

检测了44例胃癌患者腹腔冲洗液中的癌胚抗原(CEA)水平,以评估其作为术后预后预测指标的有效性。21例浆膜侵犯患者中有17例(80.9%)CEA水平升高,而大多数无浆膜侵犯的患者(22/23)CEA水平较低且未发生腹膜转移。所有细胞学检查阳性的患者腹腔冲洗液中CEA水平均升高。因此,腹腔冲洗液中的CEA水平可作为预测胃癌术后预后的辅助工具。

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CEA levels in peritoneal washings from gastric cancer patients as a prognostic guide.胃癌患者腹腔灌洗液中的癌胚抗原水平作为预后指标。
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引用本文的文献

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Evaluation of peritoneal Carcinoembryonic Antigen as a survival prognostic factor in gastric cancer patients: a single western center experience.评估腹腔内癌胚抗原作为胃癌患者生存预后因素:单西医疗中心经验。
Updates Surg. 2023 Aug;75(5):1211-1217. doi: 10.1007/s13304-023-01542-3. Epub 2023 Jun 22.
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PROGNOSTIC VALUE OF CARCINOEMBRYONIC ANTIGEN LEVELS IN TRANSOPERATIVE PERITONEAL LAVAGE IN PATIENTS WITH GASTRIC CANCER.癌胚抗原水平在胃癌患者术中腹腔灌洗中的预后价值
Arq Bras Cir Dig. 2018 Jun 21;31(1):e1358. doi: 10.1590/0102-672020180001e1358.
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Peritoneal carcinoembryonic antigen level for predicting locoregional and distant spread of gastric cancer.
用于预测胃癌局部区域和远处扩散的腹膜癌胚抗原水平。
Surg Today. 2005;35(11):919-24. doi: 10.1007/s00595-005-3057-9.
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Detection of carcinoembryonic antigen-expressing free tumor cells in peritoneal washes from patients with gastric carcinoma by polymerase chain reaction.通过聚合酶链反应检测胃癌患者腹腔灌洗液中表达癌胚抗原的游离肿瘤细胞。
Jpn J Cancer Res. 1997 Jul;88(7):687-92. doi: 10.1111/j.1349-7006.1997.tb00437.x.