Pega Frank, Liu Sze Yan, Walter Stefan, Lhachimi Stefan K
Public Health, University of Otago, 23A Mein Street, Newtown, Wellington, New Zealand, 6242.
Cochrane Database Syst Rev. 2015 Sep 11;2015(9):CD011247. doi: 10.1002/14651858.CD011247.pub2.
Unconditional cash transfers (UCTs) are a common social protection intervention that increases income, a key social determinant of health, in disaster contexts in low- and middle-income countries (LMICs).
To assess the effects of UCTs in improving health services use, health outcomes, social determinants of health, health care expenditure, and local markets and infrastructure in LMICs. We also compared the relative effectiveness of UCTs delivered in-hand with in-kind transfers, conditional cash transfers, and UCTs paid through other mechanisms.
We searched 17 academic databases, including the Cochrane Public Health Group Specialised Register, the Cochrane Database of Systematic Reviews (The Cochrane Library 2014, Issue 7), MEDLINE, and EMBASE between May and July 2014 for any records published up until 4 May 2014. We also searched grey literature databases, organisational websites, reference lists of included records, and academic journals, as well as seeking expert advice.
We included randomised and quasi-randomised controlled trials (RCTs), as well as cohort, interrupted time series, and controlled before-and-after studies (CBAs) on UCTs in LMICs. Primary outcomes were the use of health services and health outcomes.
Two authors independently screened all potentially relevant records for inclusion criteria, extracted the data, and assessed the included studies' risk of bias. We requested missing information from the study authors.
Three studies (one cluster-RCT and two CBAs) comprising a total of 13,885 participants (9640 children and 4245 adults) as well as 1200 households in two LMICs (Nicaragua and Niger) met the inclusion criteria. They examined five UCTs between USD 145 and USD 250 (or more, depending on household characteristics) that were provided by governmental, non-governmental or research organisations during experiments or pilot programmes in response to droughts. Two studies examined the effectiveness of UCTs, and one study examined the relative effectiveness of in-hand UCTs compared with in-kind transfers and UCTs paid via mobile phone. Due to the methodologic limitations of the retrieved records, which carried a high risk of bias and very serious indirectness, we considered the body of evidence to be of very low overall quality and thus very uncertain across all outcomes.Depending on the specific health services use and health outcomes examined, the included studies either reported no evidence that UCTs had impacted the outcome, or they reported that UCTs improved the outcome. No single outcome was reported by more than one study. There was a very small increase in the proportion of children who received vitamin or iron supplements (mean difference (MD) 0.10 standard deviations (SDs), 95% confidence interval (CI) 0.06 to 0.14) and on the child's home environment, as well as clinically meaningful, very large reductions in the chance of child death (hazard ratio (HR) 0.26, 95% CI 0.10 to 0.66) and the incidence of severe acute malnutrition (HR 0.44, 95% CI 0.24 to 0.80). There was also a moderate reduction in the number of days children spent sick in bed (MD - 0.36 SDs, 95% CI - 0.62 to - 0.10). There was no evidence for any effect on the proportion of children receiving deworming drugs, height for age among children, adults' level of depression, or the quality of parenting behaviour. No adverse effects were identified. The included comparisons did not examine several important outcomes, including food security and equity impacts.With regard to the relative effectiveness of UCTs compared with a food transfer providing a relatively high total caloric value, there was no evidence that a UCT had any effect on the chance of child death (HR 2.27, 95% CI 0.69 to 7.44) or severe acute malnutrition (HR 1.15, 95% CI 0.67 to 1.99). A UCT paid in-hand led to a clinically meaningful, moderate increase in the household dietary diversity score, compared with the same UCT paid via mobile phone (difference-in-differences estimator 0.43 scores, 95% CI 0.06 to 0.80), but there was no evidence for an effect on social determinants of health, health service expenditure, or local markets and infrastructure.
AUTHORS' CONCLUSIONS: Additional high-quality evidence (especially RCTs of humanitarian disaster contexts other than droughts) is required to reach clear conclusions regarding the effectiveness and relative effectiveness of UCTs for improving health services use and health outcomes in humanitarian disasters in LMICs.
无条件现金转移(UCTs)是一种常见的社会保护干预措施,在低收入和中等收入国家(LMICs)的灾害背景下,它能增加收入,而收入是健康的关键社会决定因素。
评估无条件现金转移在改善低收入和中等收入国家的卫生服务利用、健康结果、健康的社会决定因素、医疗保健支出以及当地市场和基础设施方面的效果。我们还比较了直接发放现金的无条件现金转移与实物转移、有条件现金转移以及通过其他机制支付的无条件现金转移的相对有效性。
我们检索了17个学术数据库,包括Cochrane公共卫生小组专业注册库、Cochrane系统评价数据库(《Cochrane图书馆》2014年第7期)、MEDLINE和EMBASE,检索时间为2014年5月至7月,检索截至2014年5月4日发表的任何记录。我们还检索了灰色文献数据库、组织网站、纳入记录的参考文献列表和学术期刊,并寻求专家建议。
我们纳入了关于低收入和中等收入国家无条件现金转移的随机和半随机对照试验(RCTs),以及队列研究、中断时间序列研究和前后对照研究(CBAs)。主要结局指标是卫生服务的利用和健康结果。
两位作者独立筛选所有可能相关的记录,以确定是否符合纳入标准,提取数据,并评估纳入研究的偏倚风险。我们向研究作者索要缺失的信息。
三项研究(一项整群随机对照试验和两项前后对照研究)共纳入13885名参与者(9640名儿童和4245名成年人)以及两个低收入和中等收入国家(尼加拉瓜和尼日尔)的1200户家庭,符合纳入标准。这些研究考察了政府、非政府或研究组织在应对干旱的实验或试点项目期间提供的五项金额在145美元至250美元之间(或更多,取决于家庭特征)的无条件现金转移。两项研究考察了无条件现金转移的有效性,一项研究考察了直接发放现金的无条件现金转移与实物转移以及通过手机支付的无条件现金转移相比的相对有效性。由于检索到的记录存在方法学局限性,存在高偏倚风险且间接性非常严重,我们认为证据总体质量非常低,因此在所有结局方面都非常不确定。根据所考察的具体卫生服务利用和健康结果,纳入研究要么报告没有证据表明无条件现金转移对结局有影响,要么报告无条件现金转移改善了结局。没有一项研究报告了不止一个结局。接受维生素或铁补充剂的儿童比例有非常小的增加(平均差(MD)0.10标准差(SDs),95%置信区间(CI)0.06至0.14),儿童家庭环境也有所改善,同时儿童死亡几率有临床上有意义的大幅降低(风险比(HR)0.26,95%CI 0.10至0.66)以及重度急性营养不良发病率大幅降低(HR 0.44,95%CI 0.24至0.80)。儿童卧床生病天数也有中度减少(MD -0.36 SDs,95%CI -0.62至 -0.10)。没有证据表明对接受驱虫药物的儿童比例、儿童年龄别身高、成年人抑郁水平或育儿行为质量有任何影响。未发现不良反应。纳入的比较未考察几个重要结局,包括粮食安全和公平影响。关于无条件现金转移与提供相对高热量的食物转移相比的相对有效性,没有证据表明无条件现金转移对儿童死亡几率(HR 2.27,95%CI 0.69至7.44)或重度急性营养不良(HR 1.15,95%CI 0.67至1.99)有任何影响。与通过手机支付相同的无条件现金转移相比,直接发放现金的无条件现金转移使家庭饮食多样性得分有临床上有意义的中度增加(差异差值估计值0.43分, 95%CI 0.06至0.80),但没有证据表明对健康的社会决定因素、卫生服务支出或当地市场和基础设施有影响。
需要更多高质量证据(特别是关于除干旱以外的人道主义灾难的随机对照试验),才能就无条件现金转移在改善低收入和中等收入国家人道主义灾难中的卫生服务利用和健康结果方面的有效性和相对有效性得出明确结论。