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[二硫化碳会引发动脉粥样硬化吗?]

[Is carbon disulfide atherogenic?].

作者信息

Mihalache C, Mihalache G, Pălămaru I

出版信息

Rev Med Chir Soc Med Nat Iasi. 1989 Oct-Dec;93(4):747-50.

PMID:2636775
Abstract

The changes in serum lipids and the histopathological aspect of aorta and blood vessels in the coronary, cerebral and renal territories were followed up in the white rat injected intraperitoneally with carbon bisulphide at various doses (5, 10, 15, 25, 75 mg/kg body weight) in subacute and chronic experiment (3, 6, 10 months). The absence of hyperlipemia and atherosclerotic lesions in aorta and coronary, renal and cerebral blood vessels were noticed.

摘要

在亚急性和慢性实验(3、6、10个月)中,对白鼠腹腔注射不同剂量(5、10、15、25、75毫克/千克体重)的二硫化碳,随后观察血清脂质变化以及冠状动脉、脑和肾血管区域的主动脉和血管的组织病理学情况。结果发现,主动脉以及冠状动脉、肾和脑血管中不存在高脂血症和动脉粥样硬化病变。

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Rev Med Chir Soc Med Nat Iasi. 1989 Oct-Dec;93(4):747-50.
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