解决学术临床前药物发现中的可重复性问题。
Tackling reproducibility in academic preclinical drug discovery.
机构信息
Center for Integrative Chemical Biology and Drug Discovery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7363, USA.
Small Molecule Discovery Center, School of Pharmacy, University of California at San Francisco, 1700 4th Street, Box 2552, San Francisco, California 94143, USA.
出版信息
Nat Rev Drug Discov. 2015 Nov;14(11):733-4. doi: 10.1038/nrd4737. Epub 2015 Sep 21.
DOI:10.1038/nrd4737
PMID:26388229
Abstract
The reproducibility of biomedical research on novel drug targets has become suspect. Here, we highlight how drug discovery centres embedded in academic institutions, but with a translational imperative, can help address this reproducibility crisis.
摘要
新兴药物靶点的生物医学研究的可重复性受到了怀疑。在这里，我们强调了嵌入学术机构但具有转化必要性的药物发现中心如何有助于解决这一可重复性危机。
Zotero 插件