Shurygina L V, Zlishcheva E I, Khablyuk V V, Kravtsova A N, Abramova N O, Zlishcheva L I, Kravtsov A A
A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
Baliz Farm, Krasnodar, Russia.
Bull Exp Biol Med. 2015 Aug;159(4):466-8. doi: 10.1007/s10517-015-2993-7. Epub 2015 Sep 21.
We studied antioxidant protective effect of comenic acid and potassium comenate in doses of 2, 4, and 8 mg/kg under conditions of oxidative stress in the brain of mice exposed to immobilization stress. Administration of potassium comenate and comenic acid in the above doses for 3 days before stress prevented the development of oxidative processes in the brain of stressed animals. The antioxidant effect of potassium comenate more pronounced.
我们研究了阿魏酸和阿魏酸钾在2、4和8mg/kg剂量下对遭受固定应激的小鼠大脑氧化应激条件下的抗氧化保护作用。在应激前3天给予上述剂量的阿魏酸钾和阿魏酸可预防应激动物大脑中氧化过程的发展。阿魏酸钾的抗氧化作用更明显。
