Shurygina L V, Zlishcheva E I, Kravtsov A A
A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
Bull Exp Biol Med. 2018 Aug;165(4):465-469. doi: 10.1007/s10517-018-4195-6. Epub 2018 Aug 18.
Using the model of cultured spinal ganglia, we demonstrated high neurotrophic activity of comenic acid and its derivatives potassium comenate and calcium comenate both under normal conditions and during oxidative stress. Calcium comenate in the norm as well as potassium and calcium comenates during oxidative stress demonstrate greater neurotrophic potency than comenic acid.
利用培养的脊髓神经节模型，我们证明了康孟酸及其衍生物康孟酸钾和康孟酸钙在正常条件下以及氧化应激期间均具有高神经营养活性。正常情况下的康孟酸钙以及氧化应激期间的康孟酸钾和康孟酸钙表现出比康孟酸更强的神经营养能力。
