• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

小叶过江藤（Lippia microphylla Cham.）及其精油的生物医学特性与潜力。

Biomedical properties and potentiality of Lippia microphylla Cham. and its essential oils.

作者信息

Simões Evelyne Rolim Braun, Santos Evelyne Alves, de Abreu Maria Carolina, Silva Jurandy do Nascimento, Nunes Nárcia Mariana Fonseca, da Costa Marcília Pinheiro, Pessoa Otília Deusdênia Loiola, Pessoa Cláudia, Ferreira Paulo Michel Pinheiro

机构信息

Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Ceará, Brasil.

Departamento de Ciências Biológicas, Campus Senador Helvídio Nunes de Barros, Universidade Federal do Piauí, Picos, Piauí, Brasil.

出版信息

J Intercult Ethnopharmacol. 2015 Jul-Sep;4(3):256-63. doi: 10.5455/jice.20150610104841. Epub 2015 Jun 26.

DOI:10.5455/jice.20150610104841
PMID:26401417
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4579491/
Abstract

Lippia microphylla Cham. (Verbenaceae) is an endemic underexploited Brazilian vegetal. This work reviewed the biological potentialities of Lippia microphylla, emphasizing the properties of essential oils (EOs) and analyzed scientific indicators about genus Lippia and L. microphylla. Databases from 1948 to the present were searched and a software (vantage point 7.1) associated with Derwent Innovation Index was used to identify the indicators of the genus Lippia, and biological activities and compounds in the L. macrophylla species. Ethnopharmacological records report use of L. microphylla leaves to treat gastrointestinal disorders, influenza, bronchitis, cough, nasal congestion, and sinusitis during vaporization, whose aromatic volatile oils are rich in monoterpenes, especially cineole, terpineol, and thymol. Other EOs have larvicidal activity on Aedes aegypti larvae, and antifungal, antibacterial and cytotoxic and antitumor action on human and murine cancer cells. Brazil is the country with more articles about Lippia species, but it deposited only 9 patents since 1993. Most of the publications about L. microphylla are concentrated in food and chemical sciences. This bioprospection helps to choice areas of interest for capital investment and to give support for Brazilian Institutions to establish cooperation and improve technological impact at the point of view of creation and innovation.

摘要

小叶过江藤（马鞭草科）是巴西一种未得到充分开发利用的本土植物。这项工作回顾了小叶过江藤的生物潜力，重点关注了其精油（EOs）的特性，并分析了关于过江藤属和小叶过江藤的科学指标。检索了1948年至今的数据库，并使用与德温特创新索引相关联的一款软件（Vantage Point 7.1）来确定过江藤属的指标以及大叶过江藤物种中的生物活性和化合物。民族药理学记录显示，小叶过江藤的叶子在汽化时可用于治疗胃肠道疾病、流感、支气管炎、咳嗽、鼻塞和鼻窦炎，其芳香挥发油富含单萜类化合物，尤其是桉叶油素、松油醇和百里香酚。其他精油对埃及伊蚊幼虫具有杀幼虫活性，对人类和小鼠癌细胞具有抗真菌、抗菌以及细胞毒性和抗肿瘤作用。巴西是关于过江藤属物种文章发表数量最多的国家，但自1993年以来仅申请了9项专利。关于小叶过江藤的大多数出版物都集中在食品和化学科学领域。这种生物勘探有助于选择资本投资感兴趣的领域，并为巴西机构在创新和创造方面建立合作以及提高技术影响力提供支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/3d28a196cbb0/JIE-4-256-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/f565e4c8070b/JIE-4-256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/b02f6a6fb6f9/JIE-4-256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ea6668484c7a/JIE-4-256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/2d8e1ef02574/JIE-4-256-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/519cd5191361/JIE-4-256-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ad671fb46323/JIE-4-256-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/e6efdddbc920/JIE-4-256-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ad65f8afcde7/JIE-4-256-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/3e2d53758486/JIE-4-256-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/3d28a196cbb0/JIE-4-256-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/f565e4c8070b/JIE-4-256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/b02f6a6fb6f9/JIE-4-256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ea6668484c7a/JIE-4-256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/2d8e1ef02574/JIE-4-256-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/519cd5191361/JIE-4-256-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ad671fb46323/JIE-4-256-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/e6efdddbc920/JIE-4-256-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/ad65f8afcde7/JIE-4-256-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/3e2d53758486/JIE-4-256-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a276/4579491/3d28a196cbb0/JIE-4-256-g012.jpg

相似文献

1
Biomedical properties and potentiality of Lippia microphylla Cham. and its essential oils.小叶过江藤（Lippia microphylla Cham.）及其精油的生物医学特性与潜力。
J Intercult Ethnopharmacol. 2015 Jul-Sep;4(3):256-63. doi: 10.5455/jice.20150610104841. Epub 2015 Jun 26.
2
Assessment of the in Vitro Antimelanoma Potential of Lippia microphylla Cham (Verbenaceae) Essential Oil.评估香根草（马鞭草科）精油的体外抗黑素瘤潜力。
Chem Biodivers. 2023 Nov;20(11):e202300717. doi: 10.1002/cbdv.202300717. Epub 2023 Nov 9.
3
Larvicidal activity of the essential oil from Lippia sidoides Cham. Against Aedes aegypti linn.假马鞭草挥发油对埃及伊蚊的杀幼虫活性
Mem Inst Oswaldo Cruz. 2003 Jun;98(4):569-71. doi: 10.1590/s0074-02762003000400027. Epub 2003 Aug 18.
4
Chemical Constituents of Essential Oil from Lippia sidoides Cham. (Verbenaceae) Leaves Cultivated in Hidrolândia, Goiás, Brazil.巴西戈亚斯州伊德罗兰迪亚种植的假马鞭（马鞭草科）叶精油的化学成分
Int J Anal Chem. 2012;2012:363919. doi: 10.1155/2012/363919. Epub 2012 Feb 23.
5
Leishmanicidal activity of carvacrol-rich essential oil from Lippia sidoides Cham.里品香叶挥发油的杀利什曼原虫活性
Biol Res. 2012;45(4):399-402. doi: 10.4067/S0716-97602012000400012.
6
Chemical composition, antitumor activity, and toxicity of essential oil from the leaves of Lippia microphylla.
Z Naturforsch C J Biosci. 2015;70(5-6):129-37. doi: 10.1515/znc-2014-4138.
7
Antioxidant activity and chemical composition of essential oils of three aromatic plants from La Rioja province.拉里奥哈省三种芳香植物精油的抗氧化活性及化学成分
Pharm Biol. 2016;54(1):168-73. doi: 10.3109/13880209.2015.1028077. Epub 2015 Apr 13.
8
Repellency and Larvicidal Activity of Essential oils from Xylopia laevigata, Xylopia frutescens, Lippia pedunculosa, and Their Individual Compounds against Aedes aegypti Linnaeus.光滑番荔枝、灌木番荔枝、长柄过江藤的精油及其单一化合物对埃及伊蚊的驱避和杀幼虫活性
Neotrop Entomol. 2017 Apr;46(2):223-230. doi: 10.1007/s13744-016-0457-z. Epub 2016 Nov 14.
9
Karyological studies in Brazilian species of Lippia L. (Verbenaceae).巴西过江藤属（马鞭草科）植物的核型研究
An Acad Bras Cienc. 2012 Dec;84(4):1029-37. doi: 10.1590/s0001-37652012005000068. Epub 2012 Nov 9.
10
Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema.从赛奥多小光壳炱（马鞭草科）叶片精油中分离得到的结构相关单萜对伞花烃、香芹酚和百里香酚可保护小鼠免受弹性蛋白酶诱导的肺气肿影响。
Molecules. 2016 Oct 20;21(10):1390. doi: 10.3390/molecules21101390.

引用本文的文献

1
Alpha-Phellandrene and Alpha-Phellandrene-Rich Essential Oils: A Systematic Review of Biological Activities, Pharmaceutical and Food Applications.α-水芹烯及富含α-水芹烯的精油：生物活性、药物及食品应用的系统评价
Life (Basel). 2022 Oct 14;12(10):1602. doi: 10.3390/life12101602.
2
Mechanistic Insights on the In Vitro Antibacterial Activity and In Vivo Hepatoprotective Effects of Aubl against Methotrexate-Induced Liver Injury.奥布尔对甲氨蝶呤诱导的肝损伤的体外抗菌活性及体内肝保护作用的机制研究
Pharmaceuticals (Basel). 2022 Apr 29;15(5):549. doi: 10.3390/ph15050549.
3
Essential oils of increase membrane permeability, disturb cell membrane integrity, and suppress quorum-sensing phenotype in bacteria.

本文引用的文献

1
Antibacterial, antioxidant, and anticholinesterase activities of plant seed extracts from Brazilian semiarid region.巴西半干旱地区植物种子提取物的抗菌、抗氧化和抗胆碱酯酶活性。
Biomed Res Int. 2013;2013:510736. doi: 10.1155/2013/510736. Epub 2013 Dec 10.
2
Further insecticidal activities of essential oils from Lippia sidoides and Croton species against Aedes aegypti L.紫茎泽兰和巴豆属植物精油对埃及伊蚊的进一步杀虫活性
Parasitol Res. 2013 May;112(5):1953-8. doi: 10.1007/s00436-013-3351-1. Epub 2013 Feb 23.
3
Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays.
精油可增加细胞膜通透性，破坏细胞膜完整性，并抑制细菌群体感应表型。
J Pharm Anal. 2019 Oct;9(5):301-311. doi: 10.1016/j.jpha.2019.03.001. Epub 2019 Mar 7.
4
Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America.生长在南美洲马鞭草科植物精油的抗菌活性和化学成分。
Molecules. 2018 Mar 1;23(3):544. doi: 10.3390/molecules23030544.
5
Physio-pharmacological Investigations About the Anti-inflammatory and Antinociceptive Efficacy of (+)-Limonene Epoxide.（+）-柠檬烯氧化物的抗炎和镇痛功效的生理药理学研究。
Inflammation. 2017 Apr;40(2):511-522. doi: 10.1007/s10753-016-0496-y.
评价天然产物的抗氧化能力：基于化学和细胞的测定方法综述。
Anal Chim Acta. 2013 Feb 6;763:1-10. doi: 10.1016/j.aca.2012.11.051. Epub 2012 Dec 5.
4
Chemical and antifungal investigations of six Lippia species (Verbenaceae) from Brazil.巴西六种泽兰属植物（马鞭草科）的化学成分和抗真菌研究。
Food Chem. 2012 Dec 1;135(3):2086-94. doi: 10.1016/j.foodchem.2012.06.077. Epub 2012 Jun 29.
5
In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa.从 Cayaponia racemosa 中分离得到的葫芦素的体外和体内抗癌特性。
Pharm Biol. 2012 Dec;50(12):1479-87. doi: 10.3109/13880209.2012.684691. Epub 2012 Sep 11.
6
Synergistic antibiotic activity of volatile compounds from the essential oil of Lippia sidoides and thymol.甜菊醇与侧柏烯精油的挥发性化合物协同抗菌活性。
Fitoterapia. 2012 Apr;83(3):508-12. doi: 10.1016/j.fitote.2011.12.024. Epub 2012 Jan 8.
7
Study of the antiproliferative potential of seed extracts from Northeastern Brazilian plants.巴西东北部植物种子提取物的抗增殖潜力研究。
An Acad Bras Cienc. 2011 Sep;83(3):1045-58. doi: 10.1590/s0001-37652011005000017. Epub 2011 Jul 15.
8
Hallmarks of cancer: the next generation.癌症的特征：下一代。
Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
9
Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells.氧化应激在紫杉醇诱导慢性粒细胞白血病K562细胞凋亡中的作用
Exp Toxicol Pathol. 2012 May;64(4):357-65. doi: 10.1016/j.etp.2010.09.010. Epub 2010 Nov 11.
10
Repellence of essential oils of aromatic plants growing in Argentina against Aedes aegypti (Diptera: Culicidae).阿根廷芳香植物精油对埃及伊蚊（双翅目：蚊科）的驱避作用。
Parasitol Res. 2011 Jan;108(1):69-78. doi: 10.1007/s00436-010-2042-4. Epub 2010 Sep 14.