Harada Yu, Lekcharoensuk Porntippa, Furuta Taro, Taniguchi Tooru
Satellite Lab., Biochemical Laboratory, Saraya Co., Ltd.
Biocontrol Sci. 2015;20(3):205-8. doi: 10.4265/bio.20.205.
Foot-and-mouth disease virus (FMDV) is an animal pathogen of great concern. It is contagious to cloven-hoofed animals and affects animals in extensive areas worldwide. In general, the primary eradication strategies for foot-and-mouth disease (FMD) in Japan are stamping out the disease and restriction of movement. It is also important to completely disinfect the infected area to prevent the spread of FMDV, including vehicles and people as well. However, there is no report on the effect of commercially available disinfectants against FMDV in a short contact time. In this study, we evaluated the virucidal effect of thirteen commercially available products, and got the following results: acidic ethanol disinfectants, alkaline cleaners and sodium hypochlorite had great effect (>3.0 log10 reduction in titer) against FMDV. On the other hand, neutral ethanol disinfectants, hand soaps, and quaternary ammonium compound sanitizers did not show great effect against FMDV. Therefore, it is presumed that acidic ethanol disinfectants are effective for human use and alkaline cleaners are effective for use in the infected environment for the control of a FMD outbreak.
口蹄疫病毒（FMDV）是一种备受关注的动物病原体。它可传染偶蹄类动物，并在全球广大地区影响动物。一般来说，日本口蹄疫（FMD）的主要根除策略是扑杀患病动物和限制动物移动。对包括车辆和人员在内的感染区域进行彻底消毒以防止FMDV传播也很重要。然而，尚无关于市售消毒剂在短接触时间内对FMDV效果的报告。在本研究中，我们评估了13种市售产品的杀病毒效果，得到以下结果：酸性乙醇消毒剂、碱性清洁剂和次氯酸钠对FMDV有显著效果（滴度降低>3.0 log10）。另一方面，中性乙醇消毒剂、洗手液和季铵化合物消毒剂对FMDV未显示出显著效果。因此，推测酸性乙醇消毒剂对人类使用有效，碱性清洁剂对在感染环境中控制FMD疫情有效。
