Bui Vuong N, Nguyen Khong V, Pham Nga T, Bui Anh N, Dao Tung D, Nguyen Thanh T, Nguyen Hoa T, Trinh Dai Q, Inui Kenjiro, Uchiumi Hiroshi, Ogawa Haruko, Imai Kunitoshi
Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan.
J Vet Med Sci. 2017 Apr 5;79(4):726-729. doi: 10.1292/jvms.16-0614. Epub 2017 Feb 18.
Acidic electrolyzed water (EW) (pH 2.6-5.8) and alkaline EW (pH 11.2-12.1) were examined as potential disinfectants against foot-and-mouth disease virus (FMDV). Using acidic EW with pH 2.6 and alkaline EW with pH >11.7, the viral titer decreased in vitro by > 4.0 log values, 2 min after the virus was mixed with EW at a 1:10 dilution. The strong virucidal effect of acidic EW (pH 2.6), but not that of alkaline EW (>11.7), seemed to depend on the chlorine level in the solution. Genetic analysis revealed that viral RNA was substantially reduced, especially by alkaline EW.
酸性电解水（EW）（pH 2.6 - 5.8）和碱性电解水（pH 11.2 - 12.1）作为口蹄疫病毒（FMDV）的潜在消毒剂进行了检测。使用pH 2.6的酸性电解水和pH>11.7的碱性电解水，病毒与电解水按1:10稀释混合2分钟后，体外病毒滴度下降超过4.0个对数单位。酸性电解水（pH 2.6）具有很强的杀病毒作用，而碱性电解水（>11.7）则不然，其杀病毒作用似乎取决于溶液中的氯含量。基因分析表明，病毒RNA大量减少，尤其是碱性电解水的作用更为明显。
