Nishith Pallavi, Mueser Kim T, Morse Gary A
Places for People: Community Alternatives for Hope, Health and Recovery.
Center for Psychiatric Rehabilitation, Departments of Occupational Therapy, Psychology, and Psychiatry, Boston University.
Psychiatr Rehabil J. 2015 Dec;38(4):314-9. doi: 10.1037/prj0000158. Epub 2015 Sep 28.
Posttraumatic stress disorder (PTSD) is common in people with a serious mental illness, but it is often not diagnosed or treated. Recent progress has been made in developing and validating interventions for PTSD in this population, but dropout from treatment can be problematic. The present study evaluated the feasibility and clinical outcomes of a Brief program (three sessions) for the treatment of PTSD in persons with a serious mental illness.
An open clinical trial was conducted to evaluate the Brief program, which comprises three individual weekly sessions and includes education about trauma and PTSD, as well as instruction in breathing retraining for the self-management of anxiety. Eighteen predominantly minority persons with serious mental illness and PTSD were enrolled in the Brief program and assessed at baseline, 1-month posttreatment, and 3-month follow-up.
Acceptability and tolerability of the program were high, with 15 of 18 (83%) study participants completing all three sessions. Interview-based and self-report assessments indicated significant reductions in PTSD symptoms, depression, and other symptoms at posttreatment, with treatment gains maintained at the 3-month follow-up.
The results suggest the Brief program may be clinically beneficial to persons with serious mental illnesses and PTSD and indicate that more rigorous research is needed to evaluate the program.
创伤后应激障碍（PTSD）在患有严重精神疾病的人群中很常见，但往往未得到诊断或治疗。最近在为该人群开发和验证PTSD干预措施方面取得了进展，但治疗中的脱落问题可能很严重。本研究评估了一个简短项目（三个疗程）治疗患有严重精神疾病的PTSD患者的可行性和临床结果。
进行了一项开放性临床试验以评估该简短项目，该项目包括每周一次的三个单独疗程，内容包括关于创伤和PTSD的教育，以及焦虑自我管理的呼吸再训练指导。18名主要为少数族裔的患有严重精神疾病和PTSD的患者参加了该简短项目，并在基线、治疗后1个月和3个月随访时进行了评估。
该项目的可接受性和耐受性很高，18名研究参与者中有15名（83%）完成了所有三个疗程。基于访谈和自我报告的评估表明，治疗后PTSD症状、抑郁和其他症状显著减轻，治疗效果在3个月随访时得以维持。
结果表明，该简短项目可能对患有严重精神疾病和PTSD的患者具有临床益处，并表明需要更严格的研究来评估该项目。
