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引用本文的文献

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Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox and STOP-Tox tests.基于转录组的指标用于化学干扰干细胞发育定量表征的定义：STOP-Tox和STOP-Tox测试的介绍
Arch Toxicol. 2017 Feb;91(2):839-864. doi: 10.1007/s00204-016-1741-8. Epub 2016 May 17.
2
Expression classifiers for developmental toxicants.发育毒性物质的表达分类器。
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Highlight report: New methods for quantification of bile canalicular dynamics.重点报告：胆管微管动力学定量分析的新方法
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Highlight report: Erroneous sample annotation in a high fraction of publicly available genome-wide expression datasets.重点报告：在很大一部分公开的全基因组表达数据集中存在样本注释错误。
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Highlight report: Interspecies extrapolation by physiologically based pharmacokinetic modeling.重点报告：基于生理药代动力学模型的种间外推
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本文引用的文献

1
Current developments in toxicology.毒理学的当前进展。
EXCLI J. 2012 Oct 31;11:692-702. eCollection 2012.
2
Transcriptomics in developmental toxicity testing.发育毒性测试中的转录组学
EXCLI J. 2013 Dec 12;12:1027-9. eCollection 2013.
3
In vitro test systems and their limitations.体外测试系统及其局限性。
EXCLI J. 2013 Dec 12;12:1024-6. eCollection 2013.
4
Toxicogenomics directory of chemically exposed human hepatocytes.化学暴露人肝细胞毒代基因组学目录。
Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16.
5
Lineage-specific regulation of epigenetic modifier genes in human liver and brain.人类肝脏和大脑中表观遗传修饰基因的谱系特异性调控。
PLoS One. 2014 Jul 23;9(7):e102035. doi: 10.1371/journal.pone.0102035. eCollection 2014.
6
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.从短暂转录组反应到神经发育紊乱：组蛋白乙酰化和甲基化作为可逆和不可逆药物作用之间表观遗传开关的作用
Arch Toxicol. 2014 Jul;88(7):1451-68. doi: 10.1007/s00204-014-1279-6. Epub 2014 Jun 17.
7
Acrylamide alters neurotransmitter induced calcium responses in murine ESC-derived and primary neurons.丙烯酰胺会改变小鼠胚胎干细胞衍生神经元和原代神经元中神经递质诱导的钙反应。
Neurotoxicology. 2014 Jul;43:117-126. doi: 10.1016/j.neuro.2014.03.010. Epub 2014 Apr 12.
8
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.在一种新型的基于干细胞的测试组合中，对影响神经嵴迁移功能损伤的药物和环境化学物质进行分析。
Arch Toxicol. 2014 May;88(5):1109-26. doi: 10.1007/s00204-014-1231-9. Epub 2014 Apr 2.
9
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.药物处理的分化干细胞中浓度依赖性转录组偏差的设计原则
Chem Res Toxicol. 2014 Mar 17;27(3):408-20. doi: 10.1021/tx400402j. Epub 2014 Jan 21.
10
Test systems of developmental toxicity: state-of-the art and future perspectives.发育毒性测试系统：现状与未来展望。
Arch Toxicol. 2013 Dec;87(12):2037-42. doi: 10.1007/s00204-013-1154-x.

Transcriptome based differentiation of harmless, teratogenetic and cytotoxic concentration ranges of valproic acid.

作者信息

Stöber Regina

机构信息

Leibniz Institut für Arbeitsforschung an der TU Dortmund, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Ardeystrasse 67, 44139 Dortmund, Germany.

出版信息

EXCLI J. 2014 Dec 11;13:1281-2. eCollection 2014.

PMID:26417342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4464487/
Abstract
摘要