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从医院污水中分离出的耐甲氧西林金黄色葡萄球菌和耐万古霉素金黄色葡萄球菌菌株中抗生素耐药性的传播。

Dissemination of antibiotic resistance in methicillin-resistant Staphylococcus aureus and vancomycin-resistant S aureus strains isolated from hospital effluents.

作者信息

Mandal Santi M, Ghosh Ananta K, Pati Bikas R

机构信息

Department of Microbiology, Vidyasagar University, Midnapore, West Bengal, India.

Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, India.

出版信息

Am J Infect Control. 2015 Dec 1;43(12):e87-8. doi: 10.1016/j.ajic.2015.08.015. Epub 2015 Oct 1.

DOI:10.1016/j.ajic.2015.08.015
PMID:26422180
Abstract

Vancomycin-resistant Staphylococcus aureus (VRSA) and methicillin-resistant S aureus (MRSA) strains were examined in hospital effluents. Most S aureus strains are resistant to methicillin (MRSA), followed by tetracycline. Approximately 15% of MRSA strains are also resistant to vancomycin (VRSA). All VRSA strains developed a VanR/VanS-regulated 2-component system of VanA-type resistance in their genome. Results indicate that there is a possibility of developing resistance to aminoglycosides by VRSA strains in the near future.

摘要

对医院污水中的耐万古霉素金黄色葡萄球菌(VRSA)和耐甲氧西林金黄色葡萄球菌(MRSA)菌株进行了检测。大多数金黄色葡萄球菌菌株对甲氧西林耐药(MRSA),其次是对四环素耐药。约15%的MRSA菌株也对万古霉素耐药(VRSA)。所有VRSA菌株在其基因组中都形成了一种由VanR/VanS调控的VanA型耐药二元系统。结果表明,VRSA菌株在不久的将来有可能对氨基糖苷类药物产生耐药性。

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