Pritchett R C, Al-Nawaiseh A M, Pritchett K K, Nethery V, Bishop P A, Green J M
Department of Nutrition, Exercise and Health Science, Central Washington University, Ellensburg, WA, USA.
Department of Sport Rehabilitation, Hashemite University, Zarqa, Jordan.
Biol Sport. 2015 Sep;32(3):249-54. doi: 10.5604/20831862.1163370. Epub 2015 Jul 31.
Sweat production is crucial for thermoregulation. However, sweating can be problematic for individuals with spinal cord injuries (SCI), as they display a blunting of sudomotor and vasomotor responses below the level of the injury. Sweat gland density and eccrine gland metabolism in SCI are not well understood. Consequently, this study examined sweat lactate (S-LA) (reflective of sweat gland metabolism), active sweat gland density (SGD), and sweat output per gland (S/G) in 7 SCI athletes and 8 able-bodied (AB) controls matched for arm ergometry VO2peak. A sweat collection device was positioned on the upper scapular and medial calf of each subject just prior to the beginning of the trial, with iodine sweat gland density patches positioned on the upper scapular and medial calf. Participants were tested on a ramp protocol (7 min per stage, 20 W increase per stage) in a common exercise environment (21±1°C, 45-65% relative humidity). An independent t-test revealed lower (p<0.05) SGD (upper scapular) for SCI (22.3 ±14.8 glands · cm(-2)) vs. AB. (41.0 ± 8.1 glands · cm(-2)). However, there was no significant difference for S/G between groups. S-LA was significantly greater (p<0.05) during the second exercise stage for SCI (11.5±10.9 mmol · l(-1)) vs. AB (26.8±11.07 mmol · l(-1)). These findings suggest that SCI athletes had less active sweat glands compared to the AB group, but the sweat response was similar (SLA, S/G) between AB and SCI athletes. The results suggest similar interglandular metabolic activity irrespective of overall sweat rate.
出汗对于体温调节至关重要。然而，出汗对于脊髓损伤（SCI）患者而言可能会成为问题，因为他们在损伤平面以下表现出汗腺运动和血管运动反应迟钝。目前对SCI患者的汗腺密度和外分泌腺代谢情况了解尚少。因此，本研究检测了7名SCI运动员和8名在手臂测力计峰值摄氧量方面相匹配的健全（AB）对照者的汗液乳酸（S-LA）（反映汗腺代谢）、活跃汗腺密度（SGD）以及每个腺体的出汗量（S/G）。在试验开始前，将汗液收集装置放置在每个受试者的肩胛上部和小腿内侧，同时将碘汗腺密度贴片贴在肩胛上部和小腿内侧。参与者在普通运动环境（21±1°C，相对湿度45 - 65%）中按照递增负荷方案（每个阶段7分钟，每个阶段增加20瓦）进行测试。独立样本t检验显示，SCI组（22.3±14.8个腺体·cm⁻²）肩胛上部的SGD低于AB组（41.0±8.1个腺体·cm⁻²）（p<0.05）。然而，两组之间的S/G没有显著差异。在第二个运动阶段，SCI组的S-LA（11.5±10.9 mmol·l⁻¹）显著高于AB组（26.8±11.07 mmol·l⁻¹）（p<0.05）。这些发现表明，与AB组相比，SCI运动员的活跃汗腺较少，但AB组和SCI运动员之间的出汗反应相似（SLA、S/G）。结果表明，无论总体出汗率如何，腺间代谢活动相似。
