Klein Jeffrey, Kuperman Michael, Haley Clinton, Barri Yousri, Chandrakantan Arun, Fischbach Bernard, Melton Larry, Rice Kim, Saim Muhammad, Yango Angelito, Klintmalm Goran, Rajagopal Arthi
Department of Nephrology (Klein, Barri, Chandrakantan, Fischbach, Melton, Rice, Saim, Yango, Rajagopal), Department of Pathology (Kuperman), Division of Infectious Diseases (Haley), and Annette C. and Harold C. Simmons Transplant Institute (Klintmalm), Baylor University Medical Center at Dallas.
Proc (Bayl Univ Med Cent). 2015 Oct;28(4):488-91. doi: 10.1080/08998280.2015.11929318.
We report a late presentation of adenovirus-induced renal allograft and bladder infection causing azotemia and hemorrhagic cystitis in a patient 5 years after simultaneous kidney-pancreas transplantation. Adenovirus has been increasingly recognized as a cause of morbidity and mortality in both solid organ and stem cell transplant recipients. We wish to emphasize the importance of early detection, as treatment options involve reduction of immunosuppression, followed by the addition of antiviral agents and supportive care.
我们报告了1例在同时进行肾胰腺移植5年后,腺病毒引起肾移植和膀胱感染导致氮质血症和出血性膀胱炎的迟发性病例。腺病毒已越来越多地被认为是实体器官和干细胞移植受者发病和死亡的原因。我们希望强调早期检测的重要性,因为治疗选择包括减少免疫抑制,随后添加抗病毒药物和支持性治疗。