基于 MnO2-酚醛树脂纳米复合材料的荧光谷胱甘肽探针。
Fluorescent glutathione probe based on MnO2-phenol formaldehyde resin nanocomposite.
机构信息
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
出版信息
Biosens Bioelectron. 2016 Mar 15;77:299-305. doi: 10.1016/j.bios.2015.09.044. Epub 2015 Sep 25.
MnO2-phenol formaldehyde resin (MnO2-PFR) nanocomposite is successfully prepared by a simple chemical reduction process. The resultant MnO2-PFR nanocomposite is well characterized. The absorption band of non-fluorescent MnO2 nanosheets overlaps well with the fluorescence emission of PFR nanoparticles. The green fluorescence of PFR in this nanocomposite can be effectively quenched by fluorescence resonance energy transfer from PFR to MnO2. In the presence of glutathione (GSH), the fluorescence of PFR could be recovered due to MnO2 was reduced to Mn(2+) by GSH. The nanocomposite can be use for detecting glutathione in blood serum.
MnO2-酚醛树脂（MnO2-PFR）纳米复合材料通过简单的化学还原过程成功制备。所得的 MnO2-PFR 纳米复合材料得到了很好的表征。无荧光 MnO2 纳米片的吸收带与 PFR 纳米粒子的荧光发射很好地重叠。在该纳米复合材料中，PFR 的绿色荧光可以通过 PFR 到 MnO2 的荧光共振能量转移有效地猝灭。在谷胱甘肽（GSH）存在的情况下，由于 GSH 将 MnO2 还原为 Mn(2+)，PFR 的荧光可以恢复。该纳米复合材料可用于检测血清中的谷胱甘肽。
Zotero 插件