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摄入和误吸的异物

Ingested and Aspirated Foreign Bodies.

作者信息

Green S Sarah

机构信息

Pediatrics, Oregon Health & Science University, Portland, OR.

出版信息

Pediatr Rev. 2015 Oct;36(10):430-6; quiz 437. doi: 10.1542/pir.36-10-430.

DOI:10.1542/pir.36-10-430
PMID:26430203
Abstract

Esophageal and aspirated foreign bodies have important clinical significance, and both should be considered carefully when the history or physical examination findings raise sufficient suspicion. The published evidence regarding the diagnosis and management of foreign body ingestion or aspiration is weighted disproportionately with observational studies, case controls, expert opinion, and systematic reviews. Most of the publications would receive a categorization of C (observational studies including case-control and cohort design) and D (expert opinion, case reports, and clinical reasoning). One of the few prospective studies examining the diagnostic evaluation of foreign body aspiration in children could be considered level B evidence (randomized clinical trials, systematic reviews, or diagnostic studies with minor limitations). This study found that the medical history is the most important predictive part of the evaluation. There is evidence for considering bronchoscopy if there is significant history suggestive of foreign body aspiration, even in the setting of normal physical examination findings. (28). Most ingested foreign bodies spontaneously pass without incident. However, special attention should be paid to objects in the esophagus as well as to batteries and magnets. Based on a systematic review of the literature (level B evidence) and the potential for rapid and life-threatening damage, batteries in the esophagus should be removed immediately. (10) Other objects, such as coins, may be observed for passage in an asymptomatic patient. In addition, given the high risk of significant complications, ingestion of high-powered magnets should be quickly and carefully evaluated. Although single magnets are likely to pass without complication, multiple magnets or magnets ingested with other metal objects can cause significant damage and should be removed if there is any concern for mural entrapment, bowel perforation, or failure to progress. (10)(16)(17)(18)(19). Lastly, another systematic review of the literature (level B evidence) about the aspiration of food objects in children suggests that this is a significant public health concern with potentially devastating consequences. Despite clear legislation and regulation by the Consumer Product Safety Commission regarding toys, there is no similar regulation of high-risk foods. The data suggest that there is opportunity for improvement in legislation about the production and packaging of high-risk items as well as in the education of caregivers. (22)

摘要

食管异物和误吸异物具有重要的临床意义,当病史或体格检查结果引发足够怀疑时,两者均应予以仔细考虑。关于异物摄入或误吸的诊断和处理的已发表证据在很大程度上依赖于观察性研究、病例对照研究、专家意见和系统评价。大多数出版物会被归类为C级(包括病例对照和队列设计的观察性研究)和D级(专家意见、病例报告和临床推理)。少数前瞻性研究之一对儿童异物误吸的诊断评估进行了考察,可被视为B级证据(随机临床试验、系统评价或有轻微局限性的诊断性研究)。该研究发现,病史是评估中最重要的预测部分。有证据表明,如果有明显提示异物误吸的病史,即使体格检查结果正常,也应考虑进行支气管镜检查。(28)大多数摄入的异物会自行顺利通过。然而,应特别关注食管内的异物以及电池和磁铁。基于对文献的系统评价(B级证据)以及快速和危及生命损害的可能性,食管内的电池应立即取出。(10)其他物体,如硬币,对于无症状患者可观察其是否通过。此外,鉴于严重并发症的高风险,应迅速且仔细地评估高功率磁铁的摄入情况。虽然单个磁铁可能无并发症地通过,但多个磁铁或与其他金属物体一起摄入的磁铁可造成严重损害,如果存在壁层嵌顿、肠穿孔或无法推进的任何担忧,均应取出。(10)(16)(17)(18)(19)。最后,另一项关于儿童食物误吸的文献系统评价(B级证据)表明,这是一个重大的公共卫生问题,可能产生毁灭性后果。尽管消费品安全委员会对玩具已有明确的立法和监管,但对于高风险食品却没有类似的规定。数据表明,在高风险物品的生产和包装立法以及护理人员教育方面仍有改进空间。(22)

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