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本文引用的文献

1
The Bacterial Etiology of Destructive Periodontal Disease: Current Concepts.破坏性牙周病的细菌病因学:当前概念
J Periodontol. 1992 Apr;63 Suppl 4S:322-331. doi: 10.1902/jop.1992.63.4s.322.
2
Periodontal health in teenagers treated with removable aligners and fixed orthodontic appliances.使用可摘矫治器和固定正畸矫治器治疗的青少年的牙周健康状况。
J Orofac Orthop. 2015 May;76(3):240-50. doi: 10.1007/s00056-015-0285-5.
3
Crevicular fluid levels of interleukin-8, interleukin-17 and soluble intercellular adhesion molecule-1 after regenerative periodontal therapy.再生性牙周治疗后龈沟液中白细胞介素-8、白细胞介素-17和可溶性细胞间黏附分子-1的水平
Eur J Dent. 2015 Jan-Mar;9(1):60-65. doi: 10.4103/1305-7456.149644.
4
Periodontal health during clear aligners treatment: a systematic review.隐形矫治器治疗期间的牙周健康:一项系统评价
Eur J Orthod. 2015 Oct;37(5):539-43. doi: 10.1093/ejo/cju083. Epub 2014 Dec 29.
5
The effect of orthodontic therapy on periodontal health: a review of the literature.正畸治疗对牙周健康的影响:文献综述
Int J Dent. 2014;2014:585048. doi: 10.1155/2014/585048. Epub 2014 May 29.
6
Atomic force microscopy of bacteria from periodontal subgingival biofilm: Preliminary study results.牙周龈下生物膜中细菌的原子力显微镜检查:初步研究结果。
Eur J Dent. 2013 Apr;7(2):152-158. doi: 10.4103/1305-7456.110155.
7
Long-term changes in microbiology and clinical periodontal variables after completion of fixed orthodontic appliances.固定正畸矫治器完成后微生物学和临床牙周变量的长期变化。
Orthod Craniofac Res. 2014 Feb;17(1):49-59. doi: 10.1111/ocr.12031. Epub 2013 Sep 1.
8
Effects of 2 bracket and ligation types on plaque retention: a quantitative microbiologic analysis with real-time polymerase chain reaction.两种托槽结扎类型对菌斑滞留的影响:实时聚合酶链反应的定量微生物分析。
Am J Orthod Dentofacial Orthop. 2013 Aug;144(2):260-7. doi: 10.1016/j.ajodo.2013.03.022.
9
Periodontal status of adult patients treated with fixed buccal appliances and removable aligners over one year of active orthodontic therapy.固定颊面管矫治器和可摘牙套治疗成人患者在一年积极正畸治疗后的牙周状况。
Angle Orthod. 2013 Jan;83(1):146-51. doi: 10.2319/031212-217.1. Epub 2012 Jun 22.
10
Periodontal health and relative quantity of subgingival Porphyromonas gingivalis during orthodontic treatment.正畸治疗期间牙周健康与龈下牙龈卟啉单胞菌的相对数量。
Angle Orthod. 2011 Jul;81(4):609-15. doi: 10.2319/082310-352.1. Epub 2011 Feb 9.

使用隐适美(®)系统和固定正畸矫治器治疗的患者的牙周健康状况:3个月的临床和微生物学评估。

Periodontal health status in patients treated with the Invisalign(®) system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation.

作者信息

Levrini Luca, Mangano Alessandro, Montanari Paola, Margherini Silvia, Caprioglio Alberto, Abbate Gian Marco

机构信息

Department of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.

Oro Cranio Facial Disease and Medicine Research Centre, University of Insubria, Varese, Italy.

出版信息

Eur J Dent. 2015 Jul-Sep;9(3):404-410. doi: 10.4103/1305-7456.163218.

DOI:10.4103/1305-7456.163218
PMID:26430371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4569994/
Abstract

OBJECTIVE

The aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign(®) system (Align Technology, Santa Clara, California).

MATERIALS AND METHODS

Seventy-seven patients were enrolled in this study and divided into three groups (Invisalign(®) group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann-Whitney test for independent groups.

RESULTS

After 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign(®) group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups.

CONCLUSION

Patients undergoing orthodontic treatment with the Invisalign(®) System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign(®) should be considered as a first treatment option in patients with risk of developing periodontal disease.

摘要

目的

本前瞻性研究旨在比较使用固定正畸矫治器和隐适美(Align Technology,加利福尼亚州圣克拉拉)系统治疗的患者的牙周健康状况及通过实时聚合酶链反应(PCR)检测到的微生物变化。

材料与方法

77名患者纳入本研究并分为三组(隐适美组、固定正畸矫治器组和对照组)。评估菌斑指数、探诊深度、探诊出血情况。通过实时PCR分析和检测总生物膜量及牙周病原体。所有这些数据在T0(治疗开始时)、T1(1个月时)和T2(3个月时)进行分析;并使用独立组的曼-惠特尼检验进行统计学比较。

结果

治疗1个月和3个月后,在使用固定正畸矫治器治疗的患者中仅发现1个含有牙周病厌氧菌的样本。与固定正畸矫治器组相比,隐适美组在牙周健康和总生物膜量方面显示出更好的结果。两组在T2时总生物膜量存在统计学显著差异(P<0.05)。

结论

与使用固定正畸矫治器治疗的患者相比,接受隐适美系统正畸治疗的患者在短期内牙周健康状况更佳。对于有患牙周病风险的患者,隐适美应被视为首选治疗方案。