Levrini Luca, Mangano Alessandro, Montanari Paola, Margherini Silvia, Caprioglio Alberto, Abbate Gian Marco
Department of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
Oro Cranio Facial Disease and Medicine Research Centre, University of Insubria, Varese, Italy.
Eur J Dent. 2015 Jul-Sep;9(3):404-410. doi: 10.4103/1305-7456.163218.
The aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign(®) system (Align Technology, Santa Clara, California).
Seventy-seven patients were enrolled in this study and divided into three groups (Invisalign(®) group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann-Whitney test for independent groups.
After 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign(®) group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups.
Patients undergoing orthodontic treatment with the Invisalign(®) System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign(®) should be considered as a first treatment option in patients with risk of developing periodontal disease.
本前瞻性研究旨在比较使用固定正畸矫治器和隐适美(Align Technology,加利福尼亚州圣克拉拉)系统治疗的患者的牙周健康状况及通过实时聚合酶链反应(PCR)检测到的微生物变化。
77名患者纳入本研究并分为三组(隐适美组、固定正畸矫治器组和对照组)。评估菌斑指数、探诊深度、探诊出血情况。通过实时PCR分析和检测总生物膜量及牙周病原体。所有这些数据在T0(治疗开始时)、T1(1个月时)和T2(3个月时)进行分析;并使用独立组的曼-惠特尼检验进行统计学比较。
治疗1个月和3个月后,在使用固定正畸矫治器治疗的患者中仅发现1个含有牙周病厌氧菌的样本。与固定正畸矫治器组相比,隐适美组在牙周健康和总生物膜量方面显示出更好的结果。两组在T2时总生物膜量存在统计学显著差异(P<0.05)。
与使用固定正畸矫治器治疗的患者相比,接受隐适美系统正畸治疗的患者在短期内牙周健康状况更佳。对于有患牙周病风险的患者,隐适美应被视为首选治疗方案。