Pilkington Stacey J, Belden Sarah, Miller Richard A
Azeal Dermatology Institute, Boulder, Colorado.
University Hospitals Regional Hospitals, Traditional Rotating Intern, Richmond Heights, Ohio.
J Clin Aesthet Dermatol. 2015 Sep;8(9):39-47.
There is a growing demand for noninvasive anti-aging products for which the periorbital region serves as a critical aspect of facial rejuvenation. This article reviews a multitude of cosmeceutical ingredients that have good scientific data, specifically for the periorbital region. Topical treatment options have exponentially grown from extensively studied retinoids, to recently developed technology, such as growth factors and peptides. With a focus on the periorbital anatomy, the authors review the mechanisms of action of topical cosmeceutical ingredients, effectiveness of ingredient penetration through the stratum corneum, and validity of clinical trials.
对于非侵入性抗衰老产品的需求日益增长，其中眼周区域是面部年轻化的关键部位。本文综述了大量有充分科学数据支持的药妆成分，特别是针对眼周区域的成分。局部治疗选择已呈指数级增长，从经过广泛研究的维甲酸，到最近开发的技术，如生长因子和肽。作者着眼于眼周解剖结构，综述了局部药妆成分的作用机制、成分透过角质层的有效性以及临床试验的有效性。
