Faculty of Science, Charles University in Prague , 2030 Hlavova, 128 43 Prague 2, Czech Republic.
Institute of Inorganic Chemistry, v.v.i., Czech Academy of Sciences , 250 68 Řež, Czech Republic.
ACS Appl Mater Interfaces. 2015 Oct 21;7(41):22980-9. doi: 10.1021/acsami.5b06233. Epub 2015 Oct 12.
This contribution reports on the preparation, characterization, and biological evaluation of electrospun polystyrene nanofiber materials engineered with a covalently grafted NO photodonor and ionically entangled tetracationic porphyrin and phthalocyanine photosensitizers. These photofunctional materials exhibit an effective and simultaneous photogeneration of two antibacterial species such as nitric oxide (NO) and singlet oxygen, O2((1)Δg) under illumination with visible light, as demonstrated by their direct detection using amperometric and time-resolved spectroscopic techniques. Dual-mode photoantibacterial action is demonstrated by antibacterial tests carried out on Escherichia coli.
本贡献报告了通过共价接枝的 NO 光供体和离子缠结的四阳离子卟啉和酞菁光敏剂对静电纺丝聚苯乙烯纳米纤维材料的制备、表征和生物学评价。这些光功能材料在可见光照射下有效且同时产生两种抗菌物质，如一氧化氮（NO）和单线态氧，O2((1)Δg)，这通过使用电流安培法和时间分辨光谱技术直接检测得到证明。通过对大肠杆菌进行的抗菌测试，证明了双模式光抗菌作用。
