Guler Olcay, Ozyurek Selahattin, Cakmak Selami, Isyar Mehmet, Mutlu Serhat, Mahirogullari Mahir
Acta Orthop Belg. 2015 Sep;81(3):420-6.
The present study aimed to review the general characteristics of 18 cases diagnosed with transient osteoporosis of the hip (TOH) in our hospital within a 3-year period and to present their follow-up results after conservative treatment. A retrospective evaluation was made of the treatment and results of follow-up of TOH cases using physical examination and laboratory findings, hip radiographs and magnetic resonance imaging (MRI) and Harris Hip Scores (HHS). The mean duration of complaints of 6 females (mean age, 34.3±4.3 years) and 12 males (mean age, 40.7±10.5 years) was 6.1±2.7 weeks before the treatment. Three female patients had a history of giving birth by cesarean delivery. None of the patients had any history of trauma. MRI revealed increased intensity in T2 sequences and decreased intensity in T1 sequences in the proximal aspect of the femur. None of the patients had subchondral collapse or intra-articular effusion. For 3 female patients who were breastfeeding, no medical therapy was given, but only hyperbaric oxygen (HBO) therapy and forearm crutches. As standard management, the other patients were prevented from weight-bearing with the use of forearm crutches and medical therapy of diclofenac sodium, acetylsalicylic acid, and risedronate sodium was administered and additional HBO therapy. Clinical and radiological improvements were observed in all patients. None of the patients had avascular necrosis (AVN) of the femoral head. There was no record of therapy-related complications. While HHS was 55.6±7.8 before the treatment, it increased to 88.8±5.8 in the 3rd month and to 96.0±1.8 in the 6th month after the treatment. This change in score over time was found to be significant.
本研究旨在回顾我院3年内确诊的18例髋关节一过性骨质疏松(TOH)患者的一般特征,并展示其保守治疗后的随访结果。采用体格检查、实验室检查结果、髋关节X线片、磁共振成像(MRI)及Harris髋关节评分(HHS)对TOH患者的治疗及随访结果进行回顾性评估。6例女性患者(平均年龄34.3±4.3岁)和12例男性患者(平均年龄40.7±10.5岁)在治疗前的平均主诉持续时间为6.1±2.7周。3例女性患者有剖宫产史。所有患者均无外伤史。MRI显示股骨近端T2序列信号增强,T1序列信号减弱。所有患者均无软骨下塌陷或关节内积液。对于3例正在哺乳的女性患者,未给予药物治疗,仅采用高压氧(HBO)治疗及前臂拐杖辅助。作为标准治疗,其他患者使用前臂拐杖避免负重,并给予双氯芬酸钠、乙酰水杨酸和利塞膦酸钠药物治疗及额外的HBO治疗。所有患者均观察到临床和影像学改善。所有患者均未发生股骨头缺血性坏死(AVN)。无治疗相关并发症记录。治疗前HHS为55.6±7.8,治疗后第3个月升至88.8±5.8,第6个月升至96.0±1.8。发现该评分随时间的变化具有显著性。