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基因组学在消除健康差距方面的作用。

Role of genomics in eliminating health disparities.

作者信息

Kashyap Meghana V, Nolan Michael, Sprouse Marc, Chakraborty Ranajit, Cross Deanna, Roby Rhonda, Vishwanatha Jamboor K

机构信息

University of Texas Southwestern Medical School, Dallas, Texas, USA.

Texas Center for Health Disparities, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA.

出版信息

J Carcinog. 2015 Sep 11;14:6. doi: 10.4103/1477-3163.165158. eCollection 2015.

DOI:10.4103/1477-3163.165158
PMID:26435701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4590179/
Abstract

The Texas Center for Health Disparities, a National Institute on Minority Health and Health Disparities Center of Excellence, presents an annual conference to discuss prevention, awareness education, and ongoing research about health disparities both in Texas and among the national population. The 2014 Annual Texas Conference on Health Disparities brought together experts in research, patient care, and community outreach on the "Role of Genomics in Eliminating Health Disparities." Rapid advances in genomics and pharmacogenomics are leading the field of medicine to use genetics and genetic risk to build personalized or individualized medicine strategies. We are at a critical juncture of ensuring such rapid advances benefit diverse populations. Relatively few forums have been organized around the theme of the role of genomics in eliminating health disparities. The conference consisted of three sessions addressing "Gene-Environment Interactions and Health Disparities," "Personalized Medicine and Elimination of Health Disparities," and "Ethics and Public Policy in the Genomic Era." This article summarizes the basic science, clinical correlates, and public health data presented by the speakers.

摘要

德克萨斯健康差异中心是美国国立少数族裔健康与健康差异研究所卓越中心,该中心每年都会举办一次会议,讨论德克萨斯州以及全国人口中的健康差异预防、意识教育和正在进行的研究。2014年德克萨斯健康差异年度会议汇聚了研究、患者护理和社区推广方面的专家,探讨“基因组学在消除健康差异中的作用”。基因组学和药物基因组学的快速发展正引领医学领域利用遗传学和遗传风险来制定个性化或个体化的医学策略。我们正处于确保这些快速发展造福不同人群的关键节点。围绕基因组学在消除健康差异中的作用这一主题组织的论坛相对较少。此次会议包括三场会议,分别讨论“基因 - 环境相互作用与健康差异”“个性化医学与消除健康差异”以及“基因组时代的伦理与公共政策”。本文总结了演讲者所展示的基础科学、临床关联和公共卫生数据。

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本文引用的文献

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Youth sport: positive and negative impact on young athletes.青少年体育运动:对年轻运动员的积极和消极影响。
Open Access J Sports Med. 2013 May 31;4:151-60. doi: 10.2147/OAJSM.S33556.
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Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.利用与电子健康记录相关联的 DNA 样本预测欧洲裔美国人和非裔美国人的华法林剂量。
Pharmacogenomics. 2012 Mar;13(4):407-18. doi: 10.2217/pgs.11.164. Epub 2012 Feb 13.
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